Results 81 to 90 of about 15,330,857 (290)

Nurses’ shift length and overtime working in 12 European countries: the association with perceived quality of care and patient safety [PDF]

, 2014
Background: Despite concerns as to whether nurses can perform reliably and effectively when working longer shifts, a pattern of two 12- to 13-hour shifts per day is becoming common in many hospitals to reduce shift to shift handovers, staffing overlap ...
Aiken, L.H., Simon, Michael, Aiken, LH, Griffiths, P., Griffiths, P,, Dall'Ora, C., Simon, M., Schoonhoven, L., Rafferty, A-M, Schoonhoven, Lisette, Ball, Jane, Rafferty, A.M., Tishelman, Carol, Rafferty, Anne-Marie, Schoonhoven, L, Dall'ora, Chiara, RN4CAST Consortium, Ball, J., Ball, J,, Griffiths, Peter, Lindqvist, Rikard, Tishelman, C., Lindqvist, R., Lindqvist, R,, Aiken, Linda H., Dall'Ora, C, Simon, M, Tishelman, C,, et al.   +28 more
core   +1 more source

Identifying Risk and Protective Factors for Shift Work Sleep Disorder: Insights from UK Biobank Night Shift Workers

Clocks & Sleep
Shift Work Sleep Disorder (SWSD) is a significant and highly prevalent condition affecting up to 48% of individuals with irregular work schedules. The diagnostic criteria for SWSD include persistent insomnia or sleepiness in relation to shift work, not ...
Jürgen Degenfellner, Susanne Strohmaier, Magdalena Zebrowska, Ingvild Saksvik-Lehouillier, Eva Schernhammer   +4 more
doaj   +1 more source

Comparing the Prevalence of Gastrointestinal Disorders between Day Workers and Shift Workers at Kerman University of Medical Sciences

Asian Pacific Journal of Environment and Cancer, 2020
Background and Aims: Shift work can lead to adverse health effects including gastrointestinal and cardiovascular disorders. The recent study aimed to compare the prevalence of gastrointestinal disorders among day work nurses, shift work nurses and office
Somayeh Rahimimoghadam, Narges Khanjani, Maryam Naderi, Raziyeh Rasekh   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Rotating shift work associated with obesity in men from northeastern Ontario [PDF]

, 2017
Introduction: While some studies have suggested associations between shift work and obesity, few have been population-based or considered multiple shift schedules.
Victoria A. Kirsh, Nancy Lightfoot, Michelle Cotterchio, Nancy Kreiger, Anne Grundy, Victoria Nadalin   +5 more
core   +1 more source

Rotating night shift work and polymorphism of genes important for the regulation of circadian rhythm

Scandinavian Journal of Work, Environment & Health, 2013
OBJECTIVE: People living in industrialized societies have developed specific working schedules during the day and at night, including permanent night shifts and rotating night shifts. The aim of this study was to examine the association between circadian
Edyta Reszka, Beata Peplonska, Edyta Wieczorek, Wojciech Sobala, Agnieszka Bukowska, Jolanta Gromadzińska, Jenny-Anne Lie, Helge Kjuus, Wojciech Wasowicz   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

The shift team formation problem in multi-shift manufacturing operations [PDF]

This paper addresses the problem of assigning operators to teams that work in single-, two-, or three-day shift systems. The problem was motivated by, and illustrated with a case situation encountered in Dutch manufacturing industry.
Suresh, Nallan C., Slomp, Jannes
core