Results 101 to 110 of about 12,843,377 (334)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

WORK VALUES, JOB INVOLVEMENT AND ORGANIZATIONAL COMMITMENT AMONG NURSES IN PRIVATE AND GOVERNMENT HOSPITAL: ITS IMPLICATION TO HOSPITAL ADMINISTRATION

, 2022
Sedfrey Keith M. Espina
openalex   +1 more source

Calculation of absolute free energy of binding for theophylline and its analogs to RNA aptamer using nonequilibrium work values

, 2007
The massively parallel computation of absolute binding free energy with a well-equilibrated system (MP-CAFEE) has been developed [H. Fujitani, Y. Tanida, M. Ito, G. Jayachandran, C. D. Snow, M. R. Shirts, E. J. Sorin, and V. S. Pande, J. Chem.
Baker, Bayly, Bennett, Berendsen, Boresch, Bustamante, Caldwell, Clore, Collin, Crooks, Crooks, Dang, Essmann, Fujitani, Gilson, Gouda, Hamelberg, Hendrix, Hermans, Hess, Hideaki Fujitani, Hoover, Jakalian, Jarzynski, Jarzynski, Jayachandran, Jenison, Jorgensen, Jorgensen, Kirkwood, Kofke, Kumar, Lindahl, Liphardt, Mahoney, Masakatsu Ito, Massoval, Mobley, Nose, Perlman, Perlman, Ritort, Shirts, Shirts, Sorin, Straatsma, Tembe, Wang, Wang, Wong, Yoshiaki Tanida, Zimmermann, Zwanzig, Åqvist   +53 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Replication Data for Value of Robots in Care work

, 2023
Vanja Mathier
openalex   +1 more source

Social Justice Through the Lens of the Cross: A Case for a Biblical Foundation of Social Work [PDF]

, 2019
Social work values social justice, as the profession promotes the well-being of society and the rights each person holds. Although social justice is a core value of social work, it is necessary to address the value’s foundation, and questioning the “why”
Kasch, Allison P
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

(In)satisfação dos valores laborais e estresse: análise de um modelo moderacional (Dis)satisfaction of working values and stress: analysis of a moderational model

Psicologia: Teoria e Pesquisa, 2013
O presente estudo objetivou testar um modelo empírico que investiga o poder moderacional da idade e do nível hierárquico sobre a relação entre a (in)satisfação dos valores do trabalho e o estresse psíquico.
Margareth Ribeiro M. S. Silva, Helenides Mendonça   +1 more
doaj  

The predictive value of individual factors, work‐related factors, and work–home interaction on burnout in female and male physicians: a longitudinal study [PDF]

, 2010
Ellen Melbye Langballe, Siw Tone Innstrand, Olaf Gjerløw Aasland, Erik Falkum   +3 more
openalex   +1 more source