Results 71 to 80 of about 513,054 (332)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Tracking Chart 2004 Commemorative Brands, USA 21008212C [PDF]

, 2004
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core   +1 more source

[Health protocol for the health surveillance of construction workers]

Giornale Italiano di Medicina del Lavoro ed Ergonomia, 2016
The construction site is a temporary work place characterized by a sequence of working phases with very different tasks and activities. Environmental and organizational conditions are changeable and not always predictable, exhibiting many dangers and health risks.
Giovanni Mosconi, Marisa Santini, Matteo Marco Riva, Giovanni De Vito, Giorgio Di Leone   +4 more
openaire   +1 more source

Feasibility and Acceptability of Workers’ Health Surveillance for Fire Fighters

Safety and Health at Work, 2011
The objective of this study was to test the feasibility and acceptability of a new workers' health surveillance (WHS) for fire fighters in a Dutch pilot-implementation project.In three fire departments, between November 2007 and February 2009, feasibility was tested with respect to i) worker intent to change health and behavior; ii) the quality of ...
Plat, Marie-Christine J., Frings-Dresen, Monique H. W., Sluiter, Judith K.   +2 more
openaire   +3 more sources

Challenges of implementing the integrated disease surveillance and response strategy in Zambia: a health worker perspective

BMC Public Health, 2017
BackgroundDespite advances in medical technology and public health practice at the global level over the past millennia, infectious diseases are still the leading causes of death in most resource limited countries.
Chomba Mandyata, Linda Kampata Olowski, W. Mutale   +2 more
semanticscholar   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Inconsistencies in Guidelines for Visual Health Surveillance of VDT Workers [PDF]

Journal of Occupational Health, 2012
Inconsistencies in Guidelines for Visual Health Surveillance of VDT Workers: María del Mar SEGUÍ, et al. Optic, Pharmacology and Anatomy Department, Public Health Research Group, University of Alicante, Spain—ObjectivesIn Europe, 25% of workers use video display terminals (VDTs). Occupational health surveillance has been considered a key element in the
Seguí Crespo, María del Mar, Ronda Pérez, Elena, Wimpenny, Peter   +2 more
openaire   +3 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Health worker knowledge of Integrated Disease Surveillance and Response standard case definitions: a cross-sectional survey at rural health facilities in Kenya

BMC Public Health, 2018
BackgroundThe correct knowledge of standard case definition is necessary for frontline health workers to diagnose suspected diseases across Africa. However, surveillance evaluations commonly assume this prerequisite.
Mitsuru Toda, D. Zurovac, I. Njeru, D. Kareko, M. Mwau, K. Morita   +5 more
semanticscholar   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source