Results 61 to 70 of about 2,625,446 (290)
It is important for construction companies to sustain a productive workforce without sacrificing its health and safety. This study aims to develop a practical judgement method to estimate the workload risk of individual construction workers.
Nobuki Hashiguchi +8 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Human-AI Collaboration: A Blessing or a Curse for Safety at Work?
Human-AI collaboration is increasingly considered an alternative to fears of automation and large-scale job loss that are typically attributed to AI. However, the current scholarly understanding of this type of collaboration falls victim to a one-sided ...
Lauren Waardenburg
doaj +1 more source
Safety Assessment for Decommissioning Worker
Nuclear power plants have a licensed lifetime. Nowadays, as the number of globally aged nuclear power plants increases, the need for research on the decommissioning of nuclear power plants is increasing.
Kim, Hyung Joon +3 more
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Sensation thresholds in electrocutaneous stimulation
Acoustic or visual warning signals for workers in hazardous situations might fail under loud and/or lowvisibility work situations. A warning system should be developed that uses electrocutaneous stimulation through textile electrodes.
Dölker Eva-Maria +5 more
doaj +1 more source
Worker safety on the farm [PDF]
"U.S. Farm Operations and Adult Farm Workers: In 2007, 2.2 million farms were in operation in the U.S. Approximately 5.3 million adults worked on U.S. farms in 2004, including 1.8 million hired workers and 3.5 million adult family members.
core
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

