Results 41 to 50 of about 2,312,121 (379)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Occupational exposure to volatile organic compounds affects microRNA profiling: Towards the identification of novel biomarkers

open access: yesToxicology Reports, 2020
In the framework of a project aimed at finding novel predictive biomarkers of VOCs exposure-related diseases, the effect of exposure to ethylbenzene, toluene, and xylene has been analyzed in a group of painters (spray- and roller-painters) working in the
Renata Sisto   +9 more
doaj   +1 more source

Some are Punished and Some are Rewarded: A Study of the Impact of Performance Pay on Job Satisfaction [PDF]

open access: yes, 2007
Using an econometric procedure that corrects for both self-selection of individuals into their preferred compensation scheme and wage endogeneity, this study investigates whether significant differences exist in the job satisfaction of individuals ...
McCausland, W. David   +2 more
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Workers’ Compensation, Wages, and the Risk of Injury [PDF]

open access: yes, 1988
[Excerpt] In many respects the structures of the workers\u27 compensation and unemployment insurance systems are similar. Each is actually a system of individual state systems. Both are financed by a payroll tax that is imperfectly experience rated. Both
Ehrenberg, Ronald G
core   +1 more source

Workers' Compensation Insurance In North America: Lessons for Victoria? [PDF]

open access: yes, 1996
Among the issues we will consider here are the following. Who carries the underwriting(insurance) risk for workers' compensation benefits? How is workers' compensation insuranceprices, and by whom?
H. Allan Hunt, Robert W. Klein
core   +2 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

Asbestos Consumption and Malignant Mesothelioma Mortality Trends in the Major User Countries

open access: yesAnnals of Global Health, 2023
Background: The causal association between mesothelioma and asbestos exposure is conclusive, and many studies have proved that the trend in asbestos use is a strong predictor of the pattern in mesothelioma cases with an adequate latency time (generally ...
Claudio Gariazzo   +2 more
doaj   +1 more source

Retirement and Medical Benefits: Who Has Both? [PDF]

open access: yes, 2013
[Excerpt] Employee compensation packages commonly include both wages and benefits. For decades, employee benefits have been used as part of the total compensation package to attract and retain highly qualified workers.
Kimbro, Lindsay B, Mayfield, Michelle B
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

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