Results 51 to 60 of about 2,312,121 (379)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Measures of Work-life Balance and Interventions of Reasonable Accommodations for the Return to Work of Cancer Survivors: A Scoping Review

open access: yesSafety and Health at Work
Background: Nearly half of patients diagnosed with cancer are in the middle of their traditional working age. The return to work after cancer entails challenges because of the cancer or treatments and associated with the workplace.
Giuliana Buresti   +7 more
doaj   +1 more source

Quantification of Tremolite in Friable Material Coming from Calabrian Ophiolitic Deposits by Infrared Spectroscopy

open access: yesJournal of Spectroscopy, 2015
The aim of this study is to identify the infrared absorption band suitable for quantifying tremolite in three powdered samples (fine, medium, and large size classes) coming from a quarry of ophiolitic friable rocks in the western part of the Calabria ...
Antonella Campopiano   +4 more
doaj   +1 more source

Retrofitting Agricultural Self-Propelled Machines with Roll-Over and Tip-Over Protective Structures

open access: yesSafety, 2021
In the agricultural sector, the loss of stability related to the use of self-propelled agricultural machinery (SPAM) has caused and continues to cause accidents, often with fatal outcomes.
Leonardo Vita   +2 more
doaj   +1 more source

The Problem of Worker Misclassification [PDF]

open access: yes, 2010
Employee misclassification is a significant problem that continues to plague the labor market. Unscrupulous and unknowing employers alike are costing individual workers and society tremendously.
Parisi, Ryan
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Are Private Automobile Insurance Companies Replacing Workers’ Compensation Coverage When the Employee/Insured is Injured in the Course and Scope of Employment by a Third-Party Tortfeasor?: Rubin v. State Farm Mutual Automobile Insurance Company [PDF]

open access: yes, 2004
[Excerpt] “Multiple sources for recovery are available for an employee who is physically injured by a third-party tortfeasor in the course and scope of employment.
Echols, Micah
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Airborne LTA Nanozeolites Characterization during the Manufacturing Process and External Sources Interaction with the Workplace Background

open access: yesNanomaterials, 2022
Engineered nanoscale amorphous silica nanomaterials are widespread and used in many industrial sectors. Currently, some types of silicon-based nanozeolites (NZs) have been synthesized, showing potential advantages compared to the analogous micro-forms ...
Riccardo Ferrante   +6 more
doaj   +1 more source

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