Results 21 to 30 of about 980,312 (268)

Amide proton transfer-weighted and arterial spin labeling imaging may improve differentiation between high-grade glioma recurrence and radiation-induced brain injury

Heliyon
Rationale and objectives: The management of tumor recurrence (TR) and radiation-induced brain injury (RIBI) poses significant challenges, necessitating the development of effective differentiation strategies.
Ling Chen, Lizhao Huang, Jinhuan Zhang, Shuanghong Li, Yao Li, Lifang Tang, Weijiao Chen, Min Wu, Tao Li   +8 more
doaj   +1 more source

Development and validation of an LDCT-based deep learning radiomics nomogram for predicting postoperative recurrence of stage Ia lung adenocarcinoma

Frontiers in Oncology
ObjectiveThis study wanted to use low-dose computed tomography (LDCT) plain scan images to create a deep learning radiomic nomogram (DLRN) to accurately predict the likelihood of recurrence after surgery in patients with stage Ia lung adenocarcinoma ...
Haimei Lan, Chaosheng Wei, Yiming Luo, Mingzhuang Liao, Hongfeng Liang, Jianli Qin, Jixing Yi, Fengming Xu, Dandan Huang, Meiqing Zhang, Qing Feng, Tao Li   +11 more
doaj   +1 more source

PANoptosis-related gene clusters and prognostic risk model in clear cell renal cell carcinoma

Frontiers in Genetics
BackgroundDespite advancements in targeted therapies, the prognosis for clear cell renal cell carcinoma (ccRCC) remains poor, particularly for metastatic cases.
Qiyue Zhao, Huadong Xie, Chaofu Li, Yanxiang Xiong, Yongyi Fan, Yuanbi Huang, Yi Zhan, Siping Zeng   +7 more
doaj   +1 more source

Blood metabolic fingerprinting of rats, subjected to subchronic lead exposure

Public Health and Toxicology, 2021
Introduction Environmental pollution with heavy metals is vital issue in the present time. Lead, as one of the environmental contaminators, deserves attention due to its applicability in human activity and its xenobiotic character. Methods In this study
Aleksei I. Chemezov, Marina P. Sutunkova, Ilzira A. Minigalieva, Svetlana V. Klinova, Iulia V. Ryabova   +4 more
doaj   +1 more source

Health‐Related Social Needs in Children With Sickle Cell Disease Are Associated With Worse Health‐Related Quality of Life

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with sickle cell disease (SCD) face multiple acute and chronic medical complications that may impact their quality of life as reported by patients themselves. Health‐related social needs (HRSNs), such as food and housing insecurity, are common in people with SCD, but the association between HRSNs and patient‐reported ...
Sarah J. Marks, Molly Sonenklar, Cerelia Donald, Cecelia Valrie, Wally Smith, India Sisler   +5 more
wiley   +1 more source

Unraveling the mechanisms of NK cell dysfunction in aging and Alzheimer’s disease: insights from GWAS and single-cell transcriptomics

Frontiers in Immunology
BackgroundAging is an important factor in the development of Alzheimer’s disease (AD). The senescent cells can be recognized and removed by NK cells. However, NK cell function is gradually inactivated with age. Therefore, this study used senescence as an
Jinwei Li, Jinwei Li, Yang Zhang, Yanwei You, Zhiwei Huang, Liya Wu, Cong Liang, Baohui Weng, Liya Pan, Yan Huang, Yushen Huang, Mengqi Yang, Mengting Lu, Rui Li, Xianlei Yan, Quan Liu, Shan Deng   +16 more
doaj   +1 more source

Cup‐Like Nuclei Is a Hallmark of DUX4/ERG Acute Lymphoblastic Leukemia and Reveals Cytoplasmic Mitochondria Accumulation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Cup‐like nuclei are a distinctive morphological feature observed in certain cases of acute lymphoblastic leukemia (ALL). We provide evidence that they characterize DUX4/ERG ALL independently of IKZF1 deletion and reveal marked mitochondrial accumulation in this ALL subset.
Chloé Arfeuille, Hugo Roux, Odile Fenneteau, Aurélie Caye‐Eude, Alexia Kinoo, Yoann Vial, André Baruchel, Marion Strullu, Elodie Lainey, Hélène Cavé   +9 more
wiley   +1 more source

Time for healthcare bodies to show they are no longer apartheid-era relics and say ‘never again’ to genocide

South African Medical Journal
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M S Moolla, L Shapiro, S El-Boraei, H Mahomed   +3 more
doaj   +1 more source

Rheosorbilact in complex intensive therapy of burn toxemia

Perioperative Medicine, 2021
Background.  Thermal injuries primarily cause coagulation necrosis and cell death with vascular thrombosis in the areas of the deepest lesion. Objective.
G Khamraeva, Kh Mukhitdinova, G Alauatdinova   +2 more
doaj   +1 more source

Genomic Diversity and Clinical Variability in Pediatric Primary Cutaneous Anaplastic Large Cell Lymphoma: A Case Series

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger, Efrat Bar‐Ilan, Victoria Marcu, Evgeny Grishin, Rinat Yacobi, Aviv Barzilai, Hana Golan, Assaf Arie Barg   +7 more
wiley   +1 more source