Results 31 to 40 of about 980,312 (268)

Machine learning and experimental validation identified autophagy signature in hepatic fibrosis

Frontiers in Immunology
BackgroundThe molecular mechanisms of hepatic fibrosis (HF), closely related to autophagy, remain unclear. This study aimed to investigate autophagy characteristics in HF.MethodsGene expression profiles (GSE6764, GSE49541 and GSE84044) were downloaded ...
Yushen Huang, Wen Luo, Zhijie Yang, Tian Lan, Xiaomou Wei, Hongwen Wu   +5 more
doaj   +1 more source

Effects of improved ultrafiltration on serum level of IL-6 and TNF-a, HCT, and cardiopulmonary function in patients with extracorporeal circulation in valve replacement [PDF]

Journal of Medical Biochemistry
Background: To investigate the effects of modified ultrafiltration in extracorporeal circulation valve replacement surgery. Methods: A total of 62 patients with valvular disease who underwent valve replacement were included.
Ning Geng, Fu Lili, Zhou Guangwei
doaj   +1 more source

Electron microscopy study on the transport of lead oxide nanoparticles into brain structures following their subchronic intranasal administration in rats

Scientific Reports, 2022
White outbred female rats were exposed intranasally to 50-µL of suspension of lead oxide nanoparticles (PbO NPs) at a concentration of 0.5 mg/mL thrice a week during six weeks.
Marina P. Sutunkova, Ilzira A. Minigalieva, Ivan G. Shelomencev, Larisa I. Privalova, Yuliya V. Ryabova, Anastasiya V. Tazhigulova, Lev A. Amromin, Regina F. Minigalieva, Yuliya M. Sutunkova, Vladimir B. Gurvich, Eugenya V. Makoveeva, Liubov V. Toropova   +11 more
doaj   +1 more source

Feasibility and Safety of Somato‐Cognitive Coordination Therapy for Cerebellar Ataxia Following Pediatric Brain Tumor Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cerebellar ataxia after pediatric brain tumor treatment can cause persistent gait, balance, and speech impairment, yet no established rehabilitation strategy exists. Somato‐cognitive coordination therapy (SCCT) is a virtual reality–guided intervention designed to promote sensorimotor integration through visually constrained reaching
Masanobu Takeuchi, Takashi Matsuzawa, Jun Yamanishi, Masahiro Yoshitomi, Junji Ikeda, Shin‐Ichi Tsujimoto, Yasuteru Yamaguchi, Norio Shiba, Dhroov Pathare, Ayumi Kato, Masahiko Hara   +10 more
wiley   +1 more source

Gig Workers [PDF]

Workplace Health & Safety, 2019
Occupational health nurses can ensure that gig workers are aware of health and safety requirements, receive appropriate training for the job, and use appropriate personal protective equipment.
openaire   +2 more sources

Prevalence of 21 Physician‐Defined Severe Toxicities Following Childhood Acute Lymphoblastic Leukemia Treatment: Australian Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, with an overall survival now surpassing 90% in developed countries. However, treatments are not without adverse effects. In this study, we apply the severe toxicity‐free survival (STFS) framework to determine the prevalence of 21 physician‐defined severe ...
Lane Collier, Brittany Grantham, Camilla Grud Nielsen, Louise Lundgren, Liv Andrés‐Jensen, Kjeld Schmiegelow, Chris Selman, Gareth Ball, Elyse Passmore, David A. Elliott, Rachel Conyers   +10 more
wiley   +1 more source

Sustained Therapeutic Efficacy of Intravenous Plasminogen Concentrate in Pediatric Patients With Type 1 Plasminogen Deficiency: An Analysis of Dosing Parameters and Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Type 1 plasminogen deficiency (PLGD‐1) is an ultra‐rare autosomal recessive disorder caused by variants in the PLG gene and affects approximately 1.6 individuals per million. The condition is characterized by decreased plasminogen levels and impaired function, resulting in fibrin‐rich lesions on mucous membranes throughout the body.
Charles Nakar, Karen Thibaudeau, Mary Mathias, Heather McDaniel, Madlen Reschke, Klaus Tenbrock, Joseph M. Parker, Amy Shapiro   +7 more
wiley   +1 more source

2.5D peritumoural radiomics predicts postoperative recurrence in stage I lung adenocarcinoma

Frontiers in Oncology
ObjectiveRadiomics can non-invasively predict the prognosis of a tumour by applying advanced imaging feature algorithms.The aim of this study was to predict the chance of postoperative recurrence by modelling tumour radiomics and peritumour radiomics and
Haimei Lan, Chaosheng Wei, Fengming Xu, Eqing Yang, Dayu Lu, Qing Feng, Tao Li   +6 more
doaj   +1 more source

Direct and Oxidative DNA Damage in a Group of Painters Exposed to VOCs: Dose – Response Relationship

Frontiers in Public Health, 2020
Volatile organic compounds (VOCs) are present in several working activities. This work is aimed at comparing oxidative stress and DNA damage biomarkers to specific VOCs in the occupational exposure of painters.
Renata Sisto, Delia Cavallo, Cinzia Lucia Ursini, Anna Maria Fresegna, Aureliano Ciervo, Raffaele Maiello, Enrico Paci, Daniela Pigini, Monica Gherardi, Andrea Gordiani, Nunziata L'Episcopo, Giovanna Tranfo, Pasquale Capone, Damiano Carbonari, Barbara Balzani, Pieranna Chiarella   +15 more
doaj   +1 more source

Rational Use of Herbal Products in Pediatric Patients Treated With Anticancer Drugs in the European Union

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction The use of herbal medical preparation (HMP) is rising among pediatric oncology patients, often to manage treatment‐related symptoms. Their effectiveness remains uncertain, and the risk of herb–drug interactions is underestimated.
Orianne Mahot, Mathieu Corvaisier, Laurence Spiesser‐Robelet, Mylène Duplan, Isabelle Pellier, Delphine Bourneau‐Martin, Séverine Derbré   +6 more
wiley   +1 more source