Results 31 to 40 of about 1,805,620 (318)

Amide proton transfer-weighted and arterial spin labeling imaging may improve differentiation between high-grade glioma recurrence and radiation-induced brain injury

Heliyon
Rationale and objectives: The management of tumor recurrence (TR) and radiation-induced brain injury (RIBI) poses significant challenges, necessitating the development of effective differentiation strategies.
Ling Chen, Lizhao Huang, Jinhuan Zhang, Shuanghong Li, Yao Li, Lifang Tang, Weijiao Chen, Min Wu, Tao Li   +8 more
doaj   +1 more source

Development and validation of an LDCT-based deep learning radiomics nomogram for predicting postoperative recurrence of stage Ia lung adenocarcinoma

Frontiers in Oncology
ObjectiveThis study wanted to use low-dose computed tomography (LDCT) plain scan images to create a deep learning radiomic nomogram (DLRN) to accurately predict the likelihood of recurrence after surgery in patients with stage Ia lung adenocarcinoma ...
Haimei Lan, Chaosheng Wei, Yiming Luo, Mingzhuang Liao, Hongfeng Liang, Jianli Qin, Jixing Yi, Fengming Xu, Dandan Huang, Meiqing Zhang, Qing Feng, Tao Li   +11 more
doaj   +1 more source

Blood metabolic fingerprinting of rats, subjected to subchronic lead exposure

Public Health and Toxicology, 2021
Introduction Environmental pollution with heavy metals is vital issue in the present time. Lead, as one of the environmental contaminators, deserves attention due to its applicability in human activity and its xenobiotic character. Methods In this study
Aleksei I. Chemezov, Marina P. Sutunkova, Ilzira A. Minigalieva, Svetlana V. Klinova, Iulia V. Ryabova   +4 more
doaj   +1 more source

Rheosorbilact in complex intensive therapy of burn toxemia

Perioperative Medicine, 2021
Background.  Thermal injuries primarily cause coagulation necrosis and cell death with vascular thrombosis in the areas of the deepest lesion. Objective.
G Khamraeva, Kh Mukhitdinova, G Alauatdinova   +2 more
doaj   +1 more source

PANoptosis-related gene clusters and prognostic risk model in clear cell renal cell carcinoma

Frontiers in Genetics
BackgroundDespite advancements in targeted therapies, the prognosis for clear cell renal cell carcinoma (ccRCC) remains poor, particularly for metastatic cases.
Qiyue Zhao, Huadong Xie, Chaofu Li, Yanxiang Xiong, Yongyi Fan, Yuanbi Huang, Yi Zhan, Siping Zeng   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Unraveling the mechanisms of NK cell dysfunction in aging and Alzheimer’s disease: insights from GWAS and single-cell transcriptomics

Frontiers in Immunology
BackgroundAging is an important factor in the development of Alzheimer’s disease (AD). The senescent cells can be recognized and removed by NK cells. However, NK cell function is gradually inactivated with age. Therefore, this study used senescence as an
Jinwei Li, Jinwei Li, Yang Zhang, Yanwei You, Zhiwei Huang, Liya Wu, Cong Liang, Baohui Weng, Liya Pan, Yan Huang, Yushen Huang, Mengqi Yang, Mengting Lu, Rui Li, Xianlei Yan, Quan Liu, Shan Deng   +16 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu, Kaitlin LaGasse, Cory D. Saucier, Kimberly Raymond, Miranda Lauher‐Charest, Lauren Crowder, Beilei Cai, Mary Lisha Paul, Denise Adams   +8 more
wiley   +1 more source

Differential diagnosis of gout and tenosynovial giant cell tumor, a case report

Современная ревматология
Gout is the most common inflammatory joint disease, related to microcrystalline arthritis. With improper or inadequate treatment, gout can lead to disability.A patient with a misdiagnosis of tophaceous gout is described in whom a differential diagnosis ...
P. I. Pyatnitskaya, E. N. Otteva, E. V. Polukhina   +2 more
doaj   +1 more source

Hospitalization Through Families’ Eyes: Comparing Inpatient Care Quality for Children With Sickle Cell Disease and Cystic Fibrosis in Canada

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Sickle cell disease (SCD) is a chronic, inherited hemoglobinopathy that requires frequent hospitalization for disease‐related complications. Canadian data on inpatient care is limited. This study compared caregiver‐reported hospital experiences of children with SCD to those with cystic fibrosis (CF), a chronic, autosomal recessive ...
Hailey M. Zwicker, Kyle Kemp, Perri Tutelman, Sharon H. J. Hou, Paul Fairie, Maria Santana, Gregory M. T. Guilcher, Taryn Fay‐McClymont, Glenda Bendiak, Wendy Pelletier, Nicola Wright, Fiona Schulte   +11 more
wiley   +1 more source