Results 61 to 70 of about 1,158,460 (311)

Crowdsourcing complex workflows under budget constraints [PDF]

open access: yes, 2015
We consider the problem of task allocation in crowdsourcing systems with multiple complex workflows, each of which consists of a set of interdependent micro-tasks. We propose Budgeteer, an algorithm to solve this problem under a budget constraint.
Huynh, Trung Dong   +4 more
core   +4 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Some aspects of computed tomography in Russia

open access: yesSouth African Journal of Radiology, 2009
None
S V Jargin, E E Jargin
doaj   +1 more source

LAKomp. Lemmatize, annotate and compare texts in non-standardized languages

open access: yesRIDE, 2023
LAKomp is a semi-automatic web-based tool developed for the annotation and comparison of historical, non-standardized texts. In contrast to other tools, LAKomp does not automate annotation but makes manual annotation simple and fast offering a semi ...
Barbara Aehnlich, Elisabeth Witzenhausen
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

How to Prepare Spectral Flow Cytometry Datasets for High Dimensional Data Analysis: A Practical Workflow

open access: yesFrontiers in Immunology, 2021
Spectral flow cytometry is an upcoming technique that allows for extensive multicolor panels, enabling simultaneous investigation of a large number of cellular parameters in a single experiment. To fully explore the resulting high-dimensional single cell
Hannah den Braanker   +6 more
doaj   +1 more source

Microbiome Helper: a Custom and Streamlined Workflow for Microbiome Research

open access: yesmSystems, 2017
As the microbiome field continues to grow, a multitude of researchers are learning how to conduct proper microbiome experiments. We outline here a streamlined and custom approach to processing samples from detailed sequencing library construction to step-
A. Comeau, G. Douglas, M. Langille
semanticscholar   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Electronic transmission of prescriptions in primary care: transformation, timing and teamwork [PDF]

open access: yesJournal of Primary Health Care, 2021
INTRODUCTIONDuring the coronavirus disease 2019 (COVID-19) pandemic lockdown in New Zealand in March 2020, there was a rapid shift to virtual consultations in primary care. This change was supported by system adjustments to enable electronic transmission
Lynn McBain   +2 more
doaj  

Satisfaction with Telemedicine for Cancer Pain Management: A Model of Care and Cross-Sectional Patient Satisfaction Study

open access: yesCurrent Oncology, 2022
Background: Since cancer pain requires complex modalities of care, the proper strategy for addressing its telemedicine-based management should be better defined.
Marco Cascella   +6 more
doaj   +1 more source

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