Results 81 to 90 of about 686,759 (258)

Requirements engineering for business workflow systems: a scenario-based approach [PDF]

, 2001
Workflow implementations require a deep understanding of business and human cooperation. Several approaches have been proposed to address this need for understanding, but largely in a descriptive way. Attempts to use them in software development have had
Strassl, Johann Gerhard, Strassl, J.G.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

common-workflow-language/cwltool: 3.1.20220623174452

, 2022
What's Changed Prevent the default value from being used when values were already passed by @kinow in https://github.com/common-workflow-language/cwltool/pull/1675 Expressiontool timer by @douglowe in https://github.com/common-workflow-language/cwltool ...
Thomas Hickman, Kapil kumar, Brad Chapman, Miguel Boland, Farah Zaib Khan, Tomoya Tanjo, Denis Yuen, Rupert Nash, Andrey Kartashov, Gijs Molenaar, Manvendra Singh, Guillermo Carrasco, Alejandro Barrera, bogdang989, Michael Kotliar, Dan Leehr, Stian Soiland-Reyes, Hervé Ménager, John Chilton, Michael R. Crusoe, boysha, Kevin Hannon, ash, Peter Amstutz, Nebojsa Tijanic, Joshua C. Randall, Pau Ruiz Safont, Chuck McCallum, James J Porter, Tijanic, Nebojsa, Chilton, John, Safont, Pau Ruiz, Spotify, kumar, Kapil, Barrera, Alejandro, Duke University, Porter, James J, Kotliar, Michael, Boland, Miguel, Carrasco, Guillermo, Yuen, Denis, McCallum, Chuck, University of Manchester, Kartashov, Andrey, Khan, Farah Zaib, Nash, Rupert; id_orcid, Edinburgh Parallel Computing Centre, Singh, Manvendra, Randall, Joshua C., Ménager, Hervé, Crusoe, Michael R., Citrix Systems, Inc., Hannon, Kevin, Molenaar, Gijs, College of Science and Engineering, Amstutz, Peter, Soiland-Reyes, Stian, Chapman, Brad, Tanjo, Tomoya, Leehr, Dan, Cincinnati Children's Hospital Medical Center, Hickman, Thomas   +61 more
core   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

IMPROVING INSTITUTIONAL SERVICES THROUGH UNIVERSITY ERP: A STUDY OF THE ACADEMIC PLANNING MODULE DEVELOPMENT AT SEEU

SEEU Review, 2017
Enterprise Resource Planning (ERP) systems are used by universities to handle the academic services and business processes while providing enhanced experience and services to students.
Chaushi Blerta Abazi, Dika Zamir, Chaushi Agron   +2 more
doaj   +1 more source

common-workflow-language/cwltool: 3.1.20221018083734

, 2022
What's Changed link to loops docs by @mr-c in https://github.com/common-workflow-language/cwltool/pull/1749 allow mypy process type to be used as by interpreted subclasses by @fmigneault in https://github.com/common-workflow-language/cwltool/pull/1746 ...
Thomas Hickman, Kapil kumar, Brad Chapman, Miguel Boland, Farah Zaib Khan, Tomoya Tanjo, Denis Yuen, Rupert Nash, Andrey Kartashov, Gijs Molenaar, Manvendra Singh, Guillermo Carrasco, Alejandro Barrera, bogdang989, Michael Kotliar, Dan Leehr, Stian Soiland-Reyes, Hervé Ménager, John Chilton, Michael R. Crusoe, boysha, Kevin Hannon, ash, Peter Amstutz, Nebojsa Tijanic, Joshua C. Randall, Pau Ruiz Safont, Chuck McCallum, James J Porter, Tijanic, Nebojsa, Chilton, John, Safont, Pau Ruiz, Spotify, kumar, Kapil, Barrera, Alejandro, Duke University, Porter, James J, Kotliar, Michael, Boland, Miguel, Carrasco, Guillermo, Yuen, Denis, McCallum, Chuck, University of Manchester, Kartashov, Andrey, Khan, Farah Zaib, Nash, Rupert; id_orcid, Edinburgh Parallel Computing Centre, Singh, Manvendra, Randall, Joshua C., Ménager, Hervé, Crusoe, Michael R., Citrix Systems, Inc., Hannon, Kevin, Molenaar, Gijs, College of Science and Engineering, Amstutz, Peter, Soiland-Reyes, Stian, Chapman, Brad, Tanjo, Tomoya, Leehr, Dan, Cincinnati Children's Hospital Medical Center, Hickman, Thomas   +61 more
core   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Hiperflow: integração do protocolo de atendimento de pacientes potencialmente hipertensos em um sistema gerenciador de workflow [PDF]

, 2003
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.Neste trabalho foi desenvolvido um sistema computacional para o auxílio médico no tratamento e diagnose da hipertensão
Sehn, Michel
core