Results 81 to 90 of about 823,231 (362)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

The bi-objective workflow satisfiability problem and workflow resiliency [PDF]

open access: yesJournal of Computer Security, 2016
A computerized workflow management system may enforce a security policy, specified in terms of authorized actions and constraints, thereby restricting which users can perform particular steps in a workflow. The existence of a security policy may mean that a workflow is unsatisfiable, in the sense that it is impossible to find a valid plan (an ...
Jason Crampton   +3 more
openaire   +3 more sources

Sistemas Workflow em processos empresariais, baseados no conhecimento, aplicando técnicas da inteligência artificial [PDF]

open access: yes, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.Este trabalho é um estudo comparativo da aplicação de técnicas de inteligência artificial, em sistemas Workflow, ou ...
Freitas Filho, Ly
core  

common-workflow-language/cwltool: 3.1.20211103193132

open access: yes, 2021
What's Changed Bump eWaterCycle/setup-singularity from 6 to 7 by @dependabot in https://github.com/common-workflow-language/cwltool/pull/1554 skip pyparsing 3.x to fix pydot; rdflib's sparql parsing by @mr-c in https://github.com/common-workflow ...
Thomas Hickman   +28 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Editorial Note

open access: yesDigital Studies, 2011
This is the second of two issues marking the return of Digital Studies/Le champ numérique after a major change in editorial offices.
Daniel O’Donnell
doaj   +1 more source

Multi-Objective Workflow Scheduling With Deep-Q-Network-Based Multi-Agent Reinforcement Learning

open access: yesIEEE Access, 2019
Cloud Computing provides an effective platform for executing large-scale and complex workflow applications with a pay-as-you-go model. Nevertheless, various challenges, especially its optimal scheduling for multiple conflicting objectives, are yet to be ...
Yuandou Wang   +7 more
semanticscholar   +1 more source

A Time-Driven Data Placement Strategy for a Scientific Workflow Combining Edge Computing and Cloud Computing [PDF]

open access: yesIEEE Transactions on Industrial Informatics, 2019
Compared to traditional distributed computing environments such as grids, cloud computing provides a more cost-effective way to deploy scientific workflows.
Bing Lin   +6 more
semanticscholar   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Surgical Workflow and Technical Tips for the Use of Intraoperative 3D Image and Navigation in Spine Surgery

open access: yesBrazilian Neurosurgery
Navigated spinal surgery and intraoperative computed tomography (CT) scans are part of the modern armamentarium of spinal surgeons, improving the safety and accuracy of the procedures, facilitating from the correct implant insertion to the access of the ...
Andrei Fernandes Joaquim   +3 more
doaj   +1 more source

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