Results 101 to 110 of about 931,190 (284)

A Taxonomy of Workflow Management Systems for Grid Computing

open access: yes, 2005
With the advent of Grid and application technologies, scientists and engineers are building more and more complex applications to manage and process large data sets, and execute scientific experiments on distributed resources.
A. Geppert   +12 more
core   +4 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

Bologna 3D: la pianificazione partecipata del Piano Strutturale Comunale

open access: yesGEOmedia, 2008
Bologna 3D: the Municipal Structural Plan partecipated planning The Bologna Municipality used 3D GIS solutions by Skyline for opening to citizens the decision process which leaded to its new urban plan (PSC): 3D prospective is enhancing understanding ...
Andrea Deiana   +3 more
doaj  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Designing for Proactive Network Configuration Analysis [PDF]

open access: yesJournal of Systemics, Cybernetics and Informatics, 2019
Human operators are an important aspect of any computing infrastructure; however, human errors in configuring systems pose reliability and security risks, which are increasingly serious as such systems grow more complex.
Magreth Mushi, Rudra Dutta
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Improving the creation and reporting of structured findings during digital pathology review

open access: yesJournal of Pathology Informatics, 2016
Background: Today, pathology reporting consists of many separate tasks, carried out by multiple people. Common tasks include dictation during case review, transcription, verification of the transcription, report distribution, and report the key findings ...
Ida Cervin   +2 more
doaj   +1 more source

A System for Deduction-based Formal Verification of Workflow-oriented Software Models

open access: yes, 2014
The work concerns formal verification of workflow-oriented software models using deductive approach. The formal correctness of a model's behaviour is considered.
Klimek, Radoslaw
core   +2 more sources

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