Results 101 to 110 of about 686,759 (258)
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
ERROR HANDLING IN INTEGRATION WORKFLOWS
Научный вестник МГТУ ГА, 2017 Simulation experiments performed while solving multidisciplinary engineering and scientific problems require joint usage of multiple software tools.
A. M. Nazarenko, A. A. Prokhorov
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Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Mapping of Utility-Scale Solar Panel Areas From 2000 to 2022 in China Using Google Earth Engine
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingSolar power generation is an effective way to reduce carbon emissions and has a wide range of applications worldwide. China's newly installed photovoltaic capacity has ranked first in the world in recent years.
Xin Lyu +7 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Bologna 3D: la pianificazione partecipata del Piano Strutturale Comunale
GEOmedia, 2008 Bologna 3D: the Municipal Structural Plan partecipated planning The Bologna Municipality used 3D GIS solutions by Skyline for opening to citizens the decision process which leaded to its new urban plan (PSC): 3D prospective is enhancing understanding ...
Andrea Deiana +3 more
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Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer
Molecular Oncology, EarlyView.New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau +9 more
wiley +1 more source
Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up
Molecular Oncology, EarlyView.This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani +7 more
wiley +1 more source
Designing for Proactive Network Configuration Analysis [PDF]
Journal of Systemics, Cybernetics and Informatics, 2019 Human operators are an important aspect of any computing infrastructure; however, human errors in configuring systems pose reliability and security risks, which are increasingly serious as such systems grow more complex.
Magreth Mushi, Rudra Dutta
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