Results 91 to 100 of about 652,594 (298)

A Hybrid Semi-Automated Workflow for Systematic and Literature Review Processes with Large Language Model Analysis

open access: yesFuture Internet
Systematic reviews (SRs) are a rigorous method for synthesizing empirical evidence to answer specific research questions. However, they are labor-intensive because of their collaborative nature, strict protocols, and typically large number of documents ...
Anjia Ye   +3 more
doaj   +1 more source

Bioinformatic Workflows for Generating Complete Plastid Genome Sequences—An Example from Cabomba (Cabombaceae) in the Context of the Phylogenomic Analysis of the Water-Lily Clade

open access: yesLife, 2018
The sequencing and comparison of plastid genomes are becoming a standard method in plant genomics, and many researchers are using this approach to infer plant phylogenetic relationships.
Michael Gruenstaeudl   +2 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

myExperiment: social networking for workflow-using e-scientists

open access: yes, 2007
We present the Taverna workflow workbench and argue that scientific workflow environments need a rich ecosystem of tools that support the scientists’ experimental lifecycle. Workflows are scientific objects in their own right, to be exchanged and reused.
De Roure, David, Goble, Carole
core   +2 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

ERROR HANDLING IN INTEGRATION WORKFLOWS

open access: yesНаучный вестник МГТУ ГА, 2017
Simulation experiments performed while solving multidisciplinary engineering and scientific problems require joint usage of multiple software tools.
A. M. Nazarenko, A. A. Prokhorov
doaj  

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Optimal deployment of geographically distributed workflow engines on the Cloud [PDF]

open access: yes, 2014
This research was pursued under the EPSRC ‘Working Together: Constraint Programming and Cloud Computing’ grant, a Royal Society Industry Fellowship ‘Bringing Science to the Cloud’, and an Amazon Web Services Education Research Grant.
Ozgur Akgun   +9 more
core   +1 more source

Mapping of Utility-Scale Solar Panel Areas From 2000 to 2022 in China Using Google Earth Engine

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Solar power generation is an effective way to reduce carbon emissions and has a wide range of applications worldwide. China's newly installed photovoltaic capacity has ranked first in the world in recent years.
Xin Lyu   +7 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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