Results 91 to 100 of about 931,190 (284)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A Hybrid Semi-Automated Workflow for Systematic and Literature Review Processes with Large Language Model Analysis

Future Internet
Systematic reviews (SRs) are a rigorous method for synthesizing empirical evidence to answer specific research questions. However, they are labor-intensive because of their collaborative nature, strict protocols, and typically large number of documents ...
Anjia Ye, Ananda Maiti, Matthew Schmidt, Scott J. Pedersen   +3 more
doaj   +1 more source

Bioinformatic Workflows for Generating Complete Plastid Genome Sequences—An Example from Cabomba (Cabombaceae) in the Context of the Phylogenomic Analysis of the Water-Lily Clade

Life, 2018
The sequencing and comparison of plastid genomes are becoming a standard method in plant genomics, and many researchers are using this approach to infer plant phylogenetic relationships.
Michael Gruenstaeudl, Nico Gerschler, Thomas Borsch   +2 more
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

ERROR HANDLING IN INTEGRATION WORKFLOWS

Научный вестник МГТУ ГА, 2017
Simulation experiments performed while solving multidisciplinary engineering and scientific problems require joint usage of multiple software tools.
A. M. Nazarenko, A. A. Prokhorov
doaj  

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Workflows

AbstractCurrently, digital reconstructions are mainly a process in one single context by interdisciplinary workgroups using expert technologies. 3D reconstructions in the humanities are primarily created within long-term interdisciplinary projects.
Sander Münster, Fabrizio Ivan Apollonio, Ina Bluemel, Federico Fallavollita, Riccardo Foschi, Marc Grellert, Marinos Ioannides, Peter Heinrich Jahn, Richard Kurdiovsky, Piotr Kuroczyński, Jan-Eric Lutteroth, Heike Messemer, Georg Schelbert   +12 more
openaire   +2 more sources

Mapping of Utility-Scale Solar Panel Areas From 2000 to 2022 in China Using Google Earth Engine

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
Solar power generation is an effective way to reduce carbon emissions and has a wide range of applications worldwide. China's newly installed photovoltaic capacity has ranked first in the world in recent years.
Xin Lyu, Xiaobing Li, Haishuo Wei, Junxu Wu, Dongliang Dang, Chenhao Zhang, Kai Wang, Anru Lou   +7 more
doaj   +1 more source