Results 61 to 70 of about 823,231 (362)
Frontiers in Immunology, 2021 Spectral flow cytometry is an upcoming technique that allows for extensive multicolor panels, enabling simultaneous investigation of a large number of cellular parameters in a single experiment. To fully explore the resulting high-dimensional single cell
Hannah den Braanker +6 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Current Oncology, 2022 Background: Since cancer pain requires complex modalities of care, the proper strategy for addressing its telemedicine-based management should be better defined.
Marco Cascella +6 more
doaj +1 more source
Toward a principled Bayesian workflow in cognitive science. [PDF]
Psychological methods, 2019 Experiments in research on memory, language, and in other areas of cognitive science are increasingly being analyzed using Bayesian methods. This has been facilitated by the development of probabilistic programming languages such as Stan, and easily ...
D. Schad, M. Betancourt, S. Vasishth
semanticscholar +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Electronic transmission of prescriptions in primary care: transformation, timing and teamwork [PDF]
Journal of Primary Health Care, 2021 INTRODUCTIONDuring the coronavirus disease 2019 (COVID-19) pandemic lockdown in New Zealand in March 2020, there was a rapid shift to virtual consultations in primary care. This change was supported by system adjustments to enable electronic transmission
Lynn McBain +2 more
doaj
Recent Applications of Artificial Intelligence in Radiotherapy: Where We Are and Beyond
Applied Sciences, 2022 In recent decades, artificial intelligence (AI) tools have been applied in many medical fields, opening the possibility of finding novel solutions for managing very complex and multifactorial problems, such as those commonly encountered in radiotherapy ...
Miriam Santoro +8 more
doaj +1 more source
Microbiome Helper: a Custom and Streamlined Workflow for Microbiome Research
mSystems, 2017 As the microbiome field continues to grow, a multitude of researchers are learning how to conduct proper microbiome experiments. We outline here a streamlined and custom approach to processing samples from detailed sequencing library construction to step-
A. Comeau, G. Douglas, M. Langille
semanticscholar +1 more source
A workflow execution platform for collaborative artifact-centric business processes
, 2014 To execute an artifact-centric process model, current workflow execution approaches require it to be converted to some existing executable language (e.g., BPEL) in order to run on a workflow system.
Yu, Jian +14 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source