Results 41 to 50 of about 1,864 (132)

“Hitting the Target, but Missing the Point” in Regulatory Impact Assessments: Does Bureaucratization Lead to Better RIAs?

Regulation &Governance, EarlyView.
ABSTRACT The extent to which Regulatory Impact Assessments (RIAs) conform to the “ideal” rational decision‐making model depends on factors such as political appropriation and the capacity of regulatory bodies. However, despite RIAs being embedded in bureaucratic settings, little research examines how the degree of formalization of RIA implementation ...
Alketa Peci, Leonardo Henrique Lima de Pilla, Flavio Saab, Luna Bouzada Flores Viana, Sergio Alonso Trigo   +4 more
wiley   +1 more source

Functional validation of a modified platelet desialylation test for immune and hereditary thrombocytopenias

Transfusion Medicine, EarlyView.
Abstract Background Thrombocytopenia arises from heterogeneous inherited and acquired disorders, and identifying the underlying platelet clearance mechanisms remains challenging. Platelet desialylation, characterised by loss of sialic acid and consequent exposure of terminal β‐galactose residues recognised by the Ashwell–Morell receptor, represents an ...
Karen Nogueira Chinoca Ziza, Thamy Caroline Silva, Mateus Domentino, Marina Cavalcanti Albuquerque Veiga Conrado, João Vitor Bernardo Oliveira, Felipe Augusto Rós, Caroline Gabe, Elyse Moritz, Akemi Chiba, Paula Villaça, Vanderson Rocha, Alfredo Mendrone‐Junior, José Bordin, Dante Langhi, Carla Luana Dinardo   +14 more
wiley   +1 more source

Freshwater Biodiversity Research in Brazil: Trends from a Systematic Review and Topic Modeling

International Review of Hydrobiology, Volume 111, Issue 2, December 2026.
ABSTRACT Brazil is a megadiverse country that hosts six major biomes and a vast freshwater network. Despite this richness, research on freshwater biodiversity has been heterogeneous across regions, communities, and time, leaving significant knowledge gaps.
Paula Caroline dos Reis Oliveira, Betina Kozlowsky‐Suzuki, Cleber Cunha Figueredo, Adriana Oliveira Medeiros, Doriedson Ferreira Gomes, Christina W. Castelo Branco, Priscilla Carvalho, Renan de Souza Rezende, Tássia Malacarne, Vivian de Mello de Cionek, Iola Gonçalves Boëchat, Paulo Henrique Costa Corgosinho, Fabrício Barreto Teresa, Rodrigo Assis de Carvalho, Larissa Corteletti da Costa, Lucia Ribeiro Rodrigues, Gustavo Stolzenberg Colares, Louise Cristina Gomes, Fabiana Schneck, Renato Tavares Martins, Thaisa Sala Michelan, Matheus Maximilian Ratz Scoarize, Rosilene Luciana Delariva, Evanilde Benedito, Björn Gücker   +24 more
wiley   +1 more source

Effectiveness of Organized Strategies to Enhance Access to Preventive Oral Cancer Screening Among High‐Risk Individuals in Brazil: A Randomized Clinical Trial in Primary Care

International Journal of Cancer, Volume 159, Issue 7, Page 1750-1758, 1 October 2026.
This randomized clinical trial evaluated the performance of organized risk‐based strategies to expand access to cancer preventive oral examination among vulnerable populations within the public health system of Rio de Janeiro, Brazil. Compared with an opportunistic approach, the organized invitation‐based oral cancer screening approaches systematically
Marcia Frias Pinto Marinho, Keith Bullia da Fonseca Simas, Patrícia Vinas Heras, Claudia Aparecida Serra da Cruz, Amanda Martins dos Santos Bessa, Mário José Romãnach, Aline Corrêa Abrahão, Maria Augusta Visconti, Michelle Agostini   +8 more
wiley   +1 more source

Methodological Approaches for Ultrasound Assessment of Peripheral and Abdominal Muscle Thickness in Intensive Care: A Scoping Review and Proposed Reporting Framework

Physiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Objective To map and synthesize methodological approaches used for ultrasound (US) assessment of peripheral (upper‐ and lower‐limb) and abdominal muscle thickness in critically ill patients, and to propose a preliminary Standard Operating Procedure (SOP) as a structured reporting framework.
Pedro Vinicius Porfirio, Wagner Souza Leite, Layane Santana Pereira Costa, Pedro Henrique de Moura, Ana Célia Oliveira dos Santos, Emanuel Fernandes Ferreira da Silva Junior, Elaine Araújo de Souza, Marismar Fernandes do Nascimento, Helga Cecilia Muniz de Souza, Shirley Lima Campos   +9 more
wiley   +1 more source

Characterization of a Portable Computed Tomography System for In Situ Analysis of Wooden Sculptures in Cultural Heritage

X-Ray Spectrometry, Volume 55, Issue 5, Page 763-777, September/October 2026.
ABSTRACT Portable X‐ray computed tomography (portable CT) has become an important tool for the non‐destructive investigation of cultural heritage objects, particularly when in situ analysis is required. This work presents the experimental characterization and application of a transportable cone‐beam CT system designed for the inspection of large and ...
Anderson de Paula, Isis Franzi, Roberta Borges, Josiane Cavalcante, Olga Araujo, Alessandra Machado, Ricardo Tadeu Lopes, Davi Ferreira de Oliveira   +7 more
wiley   +1 more source

A MassQL‐Based Framework for Rule‐Guided MS/MS Class‐Level Retrieval and Analog Discovery of Cannabinoids

Rapid Communications in Mass Spectrometry, Volume 40, Issue 16, 30 August 2026.
ABSTRACT Rationale Cannabinoids comprise a chemically diverse group of meroterpenoids whose extensive isomerism, variable side‐chain length, and frequent oxidative or rearranged derivatives lead to strongly overlapping yet characteristic MS/MS fragmentation patterns. In untargeted LC–MS/MS datasets, this combination of structural diversity and spectral
Julia Maia Galvão de Queiroz, Fernanda Oliveira Chagas, Valdir Florêncio Veiga‐Júnior, Monica Costa Padilha, Ricardo M. Borges   +4 more
wiley   +1 more source

Underexplored Ligand‐Binding Features of FabI From Staphylococcus aureus and Escherichia coli: A Comparative Pharmacophoric Modeling and Surface Mapping Approach

ChemMedChem, Volume 21, Issue 15, 14 August 2026.
Antimicrobial resistance highlights the urgent need for novel FabI inhibitors. Using an integrated computational approach combining ConPhar pharmacophore modeling, FTMap surface mapping, and PLIP interaction profiling across experimental structures and structures from MD simulations, we identified a conserved binding core (Y156/Y157, A95) and ...
Pedro Tenório T. F. Leite, Lucas H. S. Ocarino, Gabriel C. Veríssimo, Philipe O. Fernandes, Dara Fernanda Pereira, Fernanda Kelly M. e Oliveira, Alberto Marbán‐González, José L. Medina‐Franco, Mateus Sá M. Serafim, Thales Kronenberger, Vinícius G. Maltarollo   +10 more
wiley   +1 more source

Gestational Feed Restriction Induces Differential Expression of Novel Long Non‐Coding RNAs in Offspring Skeletal Muscle

Animal Genetics, Volume 57, Issue 4, August 2026.
ABSTRACT This study aimed to investigate how maternal feed restriction at different gestational stages alters the expression of novel long non‐coding RNAs (lncRNAs) in the skeletal muscle of goat offspring. LncRNAs are emerging as important regulators of biological processes, including myogenesis, yet their role in fetal programming remains largely ...
Maria M. M. Muniz, Thaís C. Costa, Lívia S. Rodrigues, Luiza V. Kladt, Luiz Jardel M. Motta, Mariana M. Lopes, Nicola V. L. Serão, Mateus P. Gionbelli, Marcio Duarte   +8 more
wiley   +1 more source

Valorization of Ficus carica Pruning Residues as Selective Botanical Insecticides: Optimized Furanocoumarin Extraction, Efficacy Against Neotropical Stink Bugs, and Mechanistic Insights via Molecular Docking

Archives of Insect Biochemistry and Physiology, Volume 122, Issue 4, August 2026.
Optimized extracts from Ficus carica pruning waste exhibit strong biological activity against major stink bug pests. Complementary in silico analyses suggest this efficacy relies on pest‐specific acetylcholinesterase inhibition, predicting a promising, pollinator‐safe alternative for sustainable agriculture.
Thais A. Almeida, Arley R. Páez, Lara T. M. Costa, Guy Smagghe, Yara M. Cardoso, Letícia M. Faria, Eugênio E. Oliveira, João Paulo V. Leite   +7 more
wiley   +1 more source