Results 61 to 70 of about 1,073,227 (356)

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Novel Aero-Engine Multi-Disciplinary Preliminary Design Optimization Framework Accounting for Dynamic System Operation and Aircraft Mission Performance

Aerospace, 2021
This paper presents a modular, flexible, extendable and fast-computational framework that implements a multidisciplinary, varying fidelity, multi-system approach for the conceptual and preliminary design of novel aero-engines.
Alexios Alexiou, Nikolaos Aretakis, Ioannis Kolias, Konstantinos Mathioudakis   +3 more
doaj   +1 more source

S-Store: Streaming Meets Transaction Processing [PDF]

, 2015
Stream processing addresses the needs of real-time applications. Transaction processing addresses the coordination and safety of short atomic computations. Heretofore, these two modes of operation existed in separate, stove-piped systems.
Aslantas, Cansu, Cetintemel, Ugur, Du, Jiang, Kraska, Tim, Madden, Samuel, Maier, David, Meehan, John, Pavlo, Andrew, Stonebraker, Michael, Tatbul, Nesime, Tufte, Kristin, Wang, Hao, Zdonik, Stan   +12 more
core   +3 more sources

UNREAL ENGINE 4 ENVIRONMENT WORKFLOW

Polytechnic and Design, 2018
In order to understand the creation of 3D environments in Unreal Engine 4 it is necessary to study conventional games and their essential elements. It is also necessary to understand both game and level designer's roles in the computer game industry. We have covered the importance of their roles along with games and computer game industry in general ...
Mačković, Damir, Bernik, Andrija
openaire   +3 more sources

Petrol engine workflow model for researching unconventional engines

IOP Conference Series: Earth and Environmental Science, 2021
Abstract The work lies with the study of petrol engines of an unconventional design with improved fuel and economic characteristics developed at the Automobile and Road Institute of Donetsk National Technical University for several decades.
A V Khimchenko, N I Mishchenko, T N Kolesnikova, V L Suprun, Yu V Yurchenko   +4 more
openaire   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Introduction to the problem of calculating the parameters of the mixing chamber of an afterburning bypass engine

Вестник Самарского университета: Аэрокосмическая техника, технологии и машиностроение, 2021
The article considers the problem of calculation accuracy when using mathematical models of gas-turbine engines of the second level of complexity, using the example of a device for mixing the flows of the core engine and the bypass duct of a gas turbine ...
O. D. Karev
doaj   +1 more source

Elastic Business Process Management: State of the Art and Open Challenges for BPM in the Cloud [PDF]

, 2014
With the advent of cloud computing, organizations are nowadays able to react rapidly to changing demands for computational resources. Not only individual applications can be hosted on virtual cloud infrastructures, but also complete business processes ...
Hoenisch, Philipp, Janiesch, Christian, Schulte, Stefan, Venugopal, Srikumar, Weber, Ingo   +4 more
core   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source