Results 31 to 40 of about 108,964 (293)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Design of EAM system for electromechanical equipments of coal mine blending into workflow technology

open access: yesGong-kuang zidonghua, 2014
In view of problems of high cost of maintenance and bad management flexibility existed in coal mine equipment management, an EAM system for electromechanical equipments was designed by blending into workflow technology and EAM idea.
ZHANG Jia, LI Cuiping, ZHONG Yua
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

A mathematical model of an order management automated system within the process of production technological preparation in aviation enterprisers

open access: yesМоделирование и анализ информационных систем, 2010
The article considers the analysis of an order management automated system used within the process of production technological preparation at the construction depart¬ment of the tool set design, its conceptual model using Petri nets is formulated, its ...
P. E. Efimova
doaj  

Implementation of Link-based DMS Supporting ISO 9001 QMS: Case Study

open access: yesKvalita Inovácia Prosperita, 2013
Document Management System supporting ISO 9001 Quality Management System is a typical application of Document Management it the enterprise environment.
Marek Kacmar
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Overview of the ATLAS distributed computing system [PDF]

open access: yesEPJ Web of Conferences, 2019
The CERN ATLAS experiment successfully uses a worldwide computing infrastructure to support the physics program during LHC Run 2. The Grid workflow system PanDA routinely manages 250 to 500 thousand concurrently running production and analysis jobs to ...
Elmsheuser Johannes   +1 more
doaj   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

The eclipse integrated computational environment

open access: yesSoftwareX, 2018
Problems in modeling and simulation require significantly different workflow management technologies from standard grid-based workflow management systems. Computational scientists typically interact with simulation software in a feedback-driven way where
Jay Jay Billings   +12 more
doaj   +1 more source

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