Results 91 to 100 of about 9,821,585 (424)
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
“Working Class Gone to Heaven”: From Working Class to Middle Class and Back
Narodna umjetnost, 2016 This paper problematizes the relationship between the working and middle classes in socialism, which was characterized by consumer culture and welfare. It also tackles the extinct middle class in the post-socialist context of the economic crisis and economically declined but politically void "new" working class.
Tea Škokić, Sanja Potkonjak
openaire +4 more sources
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
PCCT: Progressive Class-Center Triplet Loss for Imbalanced Medical Image Classification [PDF]
arXiv, 2022 Imbalanced training data is a significant challenge for medical image classification. In this study, we propose a novel Progressive Class-Center Triplet (PCCT) framework to alleviate the class imbalance issue particularly for diagnosis of rare diseases, mainly by carefully designing the triplet sampling strategy and the triplet loss formation ...
arxiv
Genre, Sexualité et Société, 2010 It was in the process of looking back on an indescribable family life that had been impossible to classify, and also through the encounter of a schoolteacher that had found his calling as an instructor – both indelibly leaving their marks on her path in ...
Rose-Marie Lagrave
doaj +1 more source
Upward Mobility and Family Relations in the Biographies of Academics From Working Classes
Studia Humanistyczne AGH, 2023 This article refers to problems that have not been explored in the Polish research space so far, namely educational opportunities and career paths for academics from working classes.
Kamil Łuczaj +1 more
doaj +1 more source
Working class gay men: Redefining community, restoring identity [PDF]
, 2004 This report presents the full results of one of a suite of three studies investigating how a range of pre-existing social and cultural factors mediate the development of gay male identity and shape the many forms of gay male social life in London today ...
Dodds, Catherine +2 more
core +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Geometric Class Field Theory [PDF]
arXiv, 2022 In this expository article we present Rosenlicht's work on geometric class field theory, which classifies abelian coverings of smooth, projective, geometrically connected curves over perfect fields.
arxiv
Raymond Williams The Working-Class Academic
PRISM, 2018 This paper highlights the continued relevance of the working-class academic Raymond Williams (31 August 1921 – 26 January 1988) to today’s students and academics.
Richard Wyatt
doaj +1 more source