Results 111 to 120 of about 7,030,750 (352)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
FEBS Letters, EarlyView.Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Navigating Academia in the ‘Welfare-class’
, 2017 The growing field of working-class studies provides a valuable narrative of the experiences of working-class academics, illustrates commonalities among such experiences and provides a space for dismantling the structural class-based disenfranchisement ...
Lovejoy, Laura, Penney, Emma
core +1 more source
, 2020 This essay examines nostalgia, idealization, and speech in poems from the latter half of the twentieth century in the US and the UK that convey working-class experience, identifying nostalgia as a binding feature of such poems and tracing it to the 18th -
Fogarty, William
core +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
, 1989 The article reviews the status of research on the Swedish working class history.
Olsson, Lars,, Edgren, Lars,
core
Introduction: Evolving Perspectives on Working-Class Literature
, 2020 The aim of this collection is to contribute to the forging of a more robust, politically useful, and theoretically elaborate understanding of working-class literature(s).
John Lennon +5 more
core +1 more source
Sociologies, 2010 Arguments demonstrating the individualisation of western societies, or the exclusion of those who stay on the margins of a vast middle class homogeneous life style, have no doubt allowed the move away from the rigid interpretations inherited from Marxism.
Nicolas Renahy
doaj