Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
America's rusted families: working-class political participation through three biological generations (1965-1997). [PDF]
Jeannet AM.
europepmc +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Working-class conservative voters in 2019: voices from a valley in northern England. [PDF]
Hart G.
europepmc +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
The Lower East Side Tenement Museum narra historias de inmigrantes que en el Lower East Side de Manhattan comenzaron sus vidas de nuevo entre los siglos XIX y XXI a través de la recreación de la que fue su trayectoria vital en apartamentos y negocios de ...
Alfredo Llopico
doaj
From 'Immoral' Users to 'Sunbed Addicts': The Media-Medical Pathologising of Working-class Consumers and Young Women in Late Twentieth-century England. [PDF]
Creed F.
europepmc +1 more source
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Jacques Maurice, El anarquismo andaluz, una vez más
Rose Duroux
doaj +1 more source
"As a psychiatry resident I am invited to explore my identity. But when I accept that invitation, I still encounter a wall." A qualitative study on inclusion experienced by psychiatry residents with a migration background, sexual minority identity and/or working-class background. [PDF]
Muller DP +3 more
europepmc +1 more source

