Results 111 to 120 of about 7,979,963 (279)

How Do COVID-19 Vaccine Policies Affect the Young Working Class in the Philippines? [PDF]

open access: yesInt J Environ Res Public Health, 2023
Estoce RHY, Ngan OMY, Calderon PEE.
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Warhol’s Working Class: Pop Art and Egalitarianism

open access: yesPanorama, 2019
Liam Considine
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Health Insurance Literacy Perceptions and the Needs of a Working-Class Community. [PDF]

open access: yesHealth Lit Res Pract, 2022
Kakar R   +4 more
europepmc   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

The Lower East Side Tenement Museum. Interpretando experiencias históricas de inmigrantes para iluminar el presente desde el respeto / The Lower East Side Tenement Museum. Analysing Experiences of Immigrants throughout History in Order to Better Understand the Present and Foster Respect

open access: yesDiferents, 2018
The Lower East Side Tenement Museum narra historias de inmigrantes que en el Lower East Side de Manhattan comenzaron sus vidas de nuevo entre los siglos XIX y XXI a través de la recreación de la que fue su trayectoria vital en apartamentos y negocios de ...
Alfredo Llopico
doaj  

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

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