Results 91 to 100 of about 7,979,963 (279)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Disparities in veterinary education: a survey comparing first-generation and continuing-generation students in Germany

open access: yesFrontiers in Veterinary Science
IntroductionAlthough university education in Germany is without tuition fees, the parental educational background influences the decision to study as well as the choice of subjects, and is linked to challenges that students face during the course of ...
Alexandra Gloria Kracht   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Diaspora italienne et identités urbaines à Tunis, xixe-xxie siècle

open access: yesDiasporas: Circulations, Migrations, Histoire, 2016
In the middle of the 19th century, Italians participated in the urban expansion of Tunis, thanks to their advantageous social positions and their presence in the building sector.
Christophe Giudice
doaj   +1 more source

British Working-Class Literature, Higher Education and Identity Politics: Elevating Working-Class Voices in New Literary Pedagogies [PDF]

open access: yes
This article interrogates the absence of working-class literature modules at the UK undergraduate level before evaluating various attempts at incorporating working-class voices and working-class literature within new and emerging literary pedagogies.
Attridge, John D.
core   +1 more source

The Emotional Politics of Making America Great Again: Trump’s Working Class Appeals [PDF]

open access: yes, 2017
Real estate developer and reality TV star Donald Trump’s election to the presidency of the U.S. was a departure from politics as usual in many ways. Most notably, Trump received more white working-class support than any Republican presidential candidate ...
Gentile, Haley   +4 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Autonomist Marxist Theory and Practice in the Current Crisis

open access: yesACME, 2013
Autonomist Marxism is a political tendency premised on the autonomy of the proletariat. Working class autonomy is manifested in the self-activity of the working class independent of formal organizations and representations, the multiplicity of forms that
Brian Marks
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Tradition and the Working Class, 1850–1950 [PDF]

open access: yes, 2011
For two days, October 25–26, 1991, about forty scholars—mostly, but not exclusively, historians—sat around a conference table in the Alumni Room of the prestigious Ecole Polytechnique in Paris and discussed “Tradition and the Working Class, 1850–1950 ...
Cohen, Lizabeth
core   +1 more source

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