Results 131 to 140 of about 7,030,750 (352)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

‘A Little Crow in the Tree’: Growing Inequality and White Working-Class Politics in the U.S.

open access: yes, 2018
There have been troubling trends in economic inequality, deprivation, and insecurity in the U.S. since the 1970s. This inequality and insecurity has left the American social fabric ‘fraying at the edges,’ in the words of Joseph Stiglitz.
Eppard, Lawrence   +2 more
core   +1 more source

The Lower East Side Tenement Museum. Interpretando experiencias históricas de inmigrantes para iluminar el presente desde el respeto / The Lower East Side Tenement Museum. Analysing Experiences of Immigrants throughout History in Order to Better Understand the Present and Foster Respect

open access: yesDiferents, 2018
The Lower East Side Tenement Museum narra historias de inmigrantes que en el Lower East Side de Manhattan comenzaron sus vidas de nuevo entre los siglos XIX y XXI a través de la recreación de la que fue su trayectoria vital en apartamentos y negocios de ...
Alfredo Llopico
doaj  

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Preparing Working-Class Academics for Success

open access: yes
I was one of Ryan and Sackrey’s Strangers in Paradise, an academic raised in a working-class family. After becoming a professor, I slowly grew to understand that being a successful faculty member requires learning a different set of survival techniques ...
Oldfield, Kenneth
core   +1 more source

White Working Class Communities in Lyon [PDF]

open access: yes, 2015
White Working Class Communities in Lyon explores the views and experiences of the majority population in the 8th arrondissement (borough) of Lyon, a diverse and dense area, and socially and economically one of the most challenged areas in the city.
Derek Pierre Christie   +1 more
core  

The Making of Swedish Working-Class Literature

open access: yes, 2017
This chapter gives an overview of the tradition of Swedish working-class literature, which incorporates an analysis of how this literature has been viewed in different ways in different contexts and at different times.
Magnus Nilsson   +3 more
core   +1 more source

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