Results 141 to 150 of about 7,030,750 (352)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

White working-class neighbourhoods:common themes and policy suggestions [PDF]

open access: yes, 2011
What does it mean to be white and working class in modern Britain? The Joseph Rowntree Foundation’s studies of traditionally white estates in Bradford, London, Coventry and Birmingham are part of a growing body of research into ‘white identities’.
Garner, Steven
core  

Jacques Maurice, El anarquismo andaluz, una vez más

open access: yesCahiers de Civilisation Espagnole Contemporaine, 2012
Rose Duroux
doaj   +1 more source

Krompašská vzbura a schopnosť katolíkov odpovedať na výzvy meniacej sa spoločnosti

open access: yesStudia Historica Brunensia, 2016
The article examines the Catholic answer to modern challenges such as industrialization, urban sprawl and the accelerated growth of the working class based on the case study of Krompachy workers revolt in 1921.
Jakub Štofaník
doaj  

The Modern Records Centre

open access: yesExchanges
The Modern Records Centre (MRC) is the leading archive in the United Kingdom for collections of national-level trades union and employers’ organisation records.
Pierre Botcherby, Rachel MacGregor
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Our Union: UAW/CAW Local 27 from 1950 to 1990

open access: yes, 2011
The post-war period witnessed dramatic changes in the lives of working-class families. Wages rose, working hours were reduced, pension plans and state social security measures offered greater protection against unemployment, illness, and old age, the ...
Jason Russell
core  

Where is class in the analysis of working-class education?

open access: yes, 2018
This chapter provides the backdrop and sets the tone for the book. It begins by scoping out some of the challenges and injustices facing working-class youth, and by highlighting some of the mismatches between the structures and processes of education and
John Smyth   +3 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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