Results 111 to 120 of about 1,284,813 (297)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Research on Oil and Gas Pipeline Leakage Detection Based on MSCNN-Transformer
Applied SciencesThe leakage detection of oil and gas is very important for the safe operation of pipelines. The existing working condition recognition methods have limitations in processing and capturing complex multi-category leakage signal characteristics. In order to
Yingtao Zhang +3 more
doaj +1 more source
Mal-estar no ambiente de trabalho: o caso do IFRN
Revista Principia, 2018 This study aims to diagnose the malaise at work in the perception of IFRN workers. The research is both descriptive and qualitative. The answers pointed out by workers demonstrate the following results: 1.
Maria Josely de Figueiredo Gomes +4 more
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Salāmat-i kār-i Īrān, 2016 Background and aims:The attitude of hospital workers toward safety culture in working domain has a direct effect on safe quality of care services to patients. Therefore, the purpose of this survey was studying the safety attitudes of the nurses of CCU in
GA shirali, M afravi, ZS nezamoldini
doaj
The scene superiority effect: object recognition in the context of natural scenes [PDF]
, 2011 Four experiments investigate the effect of background scene semantics on object recognition. Although past research has found that semantically consistent scene backgrounds can facilitate recognition of a target object, these claims have been challenged
Yao, Richard
core
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Left lateralization in autobiographical memory: An fMRI study using the expert archival paradigm [PDF]
, 2007 In brain-imaging and behavioural research, studies of autobiographical memory have higher ecological validity than controlled laboratory memory studies. However, they also have less controllability over the variables investigated. Here we present a novel
Campitelli, G +3 more
core
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source