Results 91 to 100 of about 12,442,445 (237)

Working conditions and health among nursing staff in Intensive Care Unit - ICU

open access: yes, 2021
The aim of this article is to analyse the nursing teams working conditions and health complaints, in the Intensive Care Unit (ICU), in a public hospital in Sao Paulo State.
Iguti, Aparecida Mari   +2 more
core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Working condition and health status of employees of the aviation enterprise

open access: yesМедицинский вестник Юга России
Objective: a hygienic assessment of working conditions and an analysis of the morbidity of aircraft workers.Materials and methods: the study was carried out on the basis of data from the Office of the Federal Service for Supervision of Consumer Rights ...
M. M. Sabitova   +4 more
doaj   +1 more source

EVALUATION OF HUMAN EXPOUSURE TO GENERATED VIBRATION FROM A GAS BOTTLE STATION [PDF]

open access: yesFiabilitate şi Durabilitate, 2015
Paper presents the analize of the working conditions of the emplo that works into a gas station. The main vibration effects to human body are presented, limit values to vibration according to actual legislation, measuring devices used for vibration ...
Ionelia CIOCAN   +3 more
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Working time patterns for sustainable work

open access: yes, 2017
Working time is a recurrent topic of study because the nature of work, its content, the conditions under which it is performed and the labour market itself keep changing.
Anxo, Dominique   +3 more
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Qualidade de vida dos profissionais do setor madeireiro de Vitória da Conquista-BA

open access: yesFloresta e Ambiente
A pesquisa foi desenvolvida no município de Vitória da Conquista, Estado da Bahia, com o objetivo de avaliar a qualidade de vida de funcionários no setor madeireiro, utilizando-se a metodologia WHOQOL-bref.
Giovanni Correia Vieira   +2 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

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