Results 131 to 140 of about 15,854,076 (410)
Molecular Oncology, Volume 19, Issue 7, Page 2120-2132, July 2025.The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld +7 more
wiley +1 more source
THE AGEING WORKFORCE IN IRELAND: WORKING CONDITIONS, HEALTH AND EXTENDING WORKING LIVES. ESRI RESEARCH SERIES NUMBER 92 OCTOBER 2019 [PDF]
, 2019 Extending working lives is a central element of active ageing policy in Ireland and Europe, and is seen as promoting active lifestyles and sustaining social protection systems in the context of an ageing population.
Maitre, Bertrand +2 more
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Molecular Oncology, Volume 19, Issue 7, Page 2038-2055, July 2025.This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou +13 more
wiley +1 more source
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic +2 more
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Molecular Oncology, EarlyView.MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin +14 more
wiley +1 more source
Working condition and health status of employees of the aviation enterprise
Медицинский вестник Юга РоссииObjective: a hygienic assessment of working conditions and an analysis of the morbidity of aircraft workers.Materials and methods: the study was carried out on the basis of data from the Office of the Federal Service for Supervision of Consumer Rights ...
M. M. Sabitova +4 more
doaj +1 more source
Working Conditions, Absence and Gender - a Multilevel Study [PDF]
In this paper we use data that combines employment records with employee survey responses to study to what extent psychosocial working conditions, measured at the work group level, relate to individual short-term and long-term sick leave.
Bokenblom, Mattias, Ekblad, Kristin
core
Greening of Industries in the EU: Anticipating and Managing the Effects on Quantity and Quality of Jobs [PDF]
, 2012 [Excerpt] All jobs will be affected as the EU moves to a green economy: new jobs will be created and some will be eliminated, but most existing jobs will be transformed.
European Foundation for the Improvement of Living and Working Conditions
core +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source