Results 131 to 140 of about 16,057,130 (409)

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

open access: yesFEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican   +7 more
wiley   +1 more source

Qualidade de vida dos profissionais do setor madeireiro de Vitória da Conquista-BA

open access: yesFloresta e Ambiente
A pesquisa foi desenvolvida no município de Vitória da Conquista, Estado da Bahia, com o objetivo de avaliar a qualidade de vida de funcionários no setor madeireiro, utilizando-se a metodologia WHOQOL-bref.
Giovanni Correia Vieira   +2 more
doaj   +1 more source

Working Conditions and Health of European Older Workers [PDF]

open access: yes
Working conditions have greatly evolved in recent decades in developed countries. This evolution has been accompanied with the appearance of new forms of work organisation that may be sources of stress and health risk for older workers.
Pascale Lengagne, Thierry Debrand
core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

open access: yesMolecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia   +17 more
wiley   +1 more source

Health at Work and Low-pay:a European Perspective [PDF]

open access: yes
This study investigates the relationship between health, working conditions and pay in Europe. In particular, we measure health at work using self-assessed indicators for overall, as well as physical and mental health, using the 2005 wave of the EWCS ...
Claudio Lucifora, Elena Cottini
core  

Employee voice and collective formation in the Indian ITES-BPO industry [PDF]

open access: yes, 2008
The growth of the information technology enabled services-business process outsourcing industry calls for attention to employees' working conditions and rights.
D'Cruz, P.   +3 more
core  

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Amanda Camacho: Columbian Cut-Flower Worker [PDF]

open access: yes, 2009
this story is part of ILRF\u27s Stories of Working Women series. In her testimony, Amanda Comacho describes the cut-flower industry, working conditions, and her daily life in Colombia.
International Labor Rights Forum
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

Revising psychosocial aspects of the nursing work

open access: yesRev Rene, 2008
The psychosocial aspects on nursing working environment have called attention because of the increasing number of absenteeism and the health problems of nursing professionals, leading to damages on the quality of assistance care.
Marcela Luísa Manetti   +2 more
doaj  

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