Results 141 to 150 of about 1,510,739 (305)

Condiciones laborales en enfermeras de Cartagena, Colombia Nurses working conditions in Cartagena, Colombia Condições de trabalho para enfermeiras de Cartagena, Colômbia

Avances en Enfermería, 2010
Objetivo: identificar las condiciones laborales del profesional de enfermería en instituciones de salud en Cartagena, Colombia. Método: se diseñó un estudio descriptivo que incluyó personal de enfermería de instituciones públicas y privadas.
Gómez Bustamante Edna, Cogollo Milanés Zuleima Cogollo Milanés   +1 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Wages and Working Conditions in the Crisis

, 2012
The economic and financial crisis of 2008–2010 has impacted on pay in most EU Member States leading to wage deceleration, pay freezes and sometimes pay cuts. The crisis hit vulnerable groups (low-skilled, young, migrants) particularly hard.
Vandekerckhove, Sem, Van Gyes, Guy, Van Peteghem, Jan   +2 more
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Musculoskeletal complaints, working conditions, and job satisfaction among Dutch orthodontists. [PDF]

Eur J Orthod
Bos A, van der Bie RM, Hardjosantoso DB, Jonkman REG, Bruers JJM.   +4 more
europepmc   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Survey on the Working Conditions, Salary, and Job Satisfaction of Employed Veterinarians in Germany. [PDF]

Vet Sci
Jensen KC, Wunderlich C, Steingräber L, Warschau M, Ewert M, Brandebusemeyer E.   +5 more
europepmc   +1 more source

Working Conditions of Migrant Women in Padua's Cleaning Sector [PDF]

openThe cleaning industry in Italy is growing and it is increasingly characterised by contracting and subcontracting dynamics that drive down the expenditure allocated to this item in public and private company budgets, such as universities, shopping ...
CILLUFFO, ROBERTA
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

The impact of working conditions on sickness absence among older workers: a systematic review. [PDF]

Eur J Ageing
Gero K, Benken C, Dragano N.
europepmc   +1 more source