Results 181 to 190 of about 13,029,186 (274)

Exploring working conditions and job stability of midwives in Spain: results from a cross-sectional national survey. [PDF]

BMC Pregnancy Childbirth
Rodríguez-Blanco N, Sánchez-Más J, Ayuso-Murillo D, Fontán-Vinagre MG, Angulo-Perea M, Díaz-Gautier A, Guerrero-Menéndez R.   +6 more
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

'Don't work more than 3 days straight': Working conditions as learning conditions in general practice. [PDF]

Clin Med (Lond)
Grant L.
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

How salary satisfaction and working conditions shape professional attitudes of primary school teachers in Vietnam: a structural equation modeling analysis during the 2024-2026 salary reform. [PDF]

Front Psychol
Le TQM, Li YJ.
europepmc   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Disparities in Working Conditions Among Maternal and Neonatal Health Personnel in a Crisis Context: The Case of the East of the Democratic Republic of Congo. [PDF]

Int J Womens Health
Mwene-Batu P, Mulume AB, Lembebu JCZ, Mary M, Ngaboyeka GA, Lurhangire EO, Bigirinama R, Chimanuka Murhima'alika C, Chiribagula CZ, Bisimwa Balaluka G, Tappis H.   +10 more
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Are Working Conditions of Nurses Associated With Nutrition, Physical Activity, and Stress Levels? [PDF]

Int Nurs Rev
Keskin E, Kalkan I.
europepmc   +1 more source