Results 201 to 210 of about 15,854,076 (410)

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren, Moana Busch, Pedro A. Ruiz, Ermanno Malagola, Valeria Baumeler, Federica Foti, Adelina Gross, Tobias Grütter, Hendrik Edel, Cordelia Schuler, Kristina Handler, Glenn De Lange, Isabelle C. Arnold, Cheryl de Vallière, Klaus Seuwen, Martin Hausmann, Gerhard Rogler   +16 more
wiley   +1 more source

EPIDEMIOLOGICAL STUDIES ON THE SYMPTOMS DUE TO STRAWBERRY CULTURE IN THE VINYL-HOUSE : 1. An Analysis of Subjective Symptoms by Working Conditions and Constitution of the Farmers

, 1979
Tatsushi Ishizaki, Sohei Makino, R Ikemori, Takeshi Fukuda, S Namai, Hisashi Yamamoto   +5 more
openalex   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Working conditions in Russia [PDF]

International Psychiatry, 2007
Amina Nazaralieva, Clare Oakley
openaire   +2 more sources

Working Conditions in Complementary and Integrative Healthcare Professions. [PDF]

J Occup Environ Med
Whitley MD, Faydenko J, Madigan D, Finnell JS.   +3 more
europepmc   +1 more source

Studies on health hazards among cooks providing school lunch service. Report 1. The influense of working conditions in central and school kitchens on the prevalence of health hazards.

, 1984
Yutaka Oze
openalex   +2 more sources

A Model to Analyze Ergonomics Working Conditions [PDF]

, 2000
Bahador Ghahramani
openalex   +1 more source

Quality of Life and Working Conditions of Plastic Surgeons and Trainees: A National Survey. [PDF]

Int J Environ Res Public Health
Dietrich LG, Deml MJ, De Pellegrin L, Zubler C.   +3 more
europepmc   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Occupational hazard of female film rolling workers and effects of improved working conditions

, 1982

openalex   +2 more sources