Results 81 to 90 of about 1,214,007 (300)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Qualidade de vida dos profissionais do setor madeireiro de Vitória da Conquista-BA

Floresta e Ambiente
A pesquisa foi desenvolvida no município de Vitória da Conquista, Estado da Bahia, com o objetivo de avaliar a qualidade de vida de funcionários no setor madeireiro, utilizando-se a metodologia WHOQOL-bref.
Giovanni Correia Vieira, Pedro Henrique Alcântara de Cerqueira, Luis Carlos de Freitas   +2 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Working conditions of a nursing team in mental health facility [PDF]

, 2021
Aline Morais, Gisele Fernandes Tarma Cordeiro, Ângela Aparecida Peters, Tatiana Marques dos Santos, Rosa Gomes dos Santos Ferreira, María Angélica de Almeida Peres   +5 more
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

The Health and Working Conditions of Women Employed in Child Care [PDF]

, 2017
Laura Linnan, Gabriela Arandia, Lori A. Bateman, Amber Vaughn, Natalie Smith, Dianne S. Ward   +5 more
openalex   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

EVALUATION OF HUMAN EXPOUSURE TO GENERATED VIBRATION FROM A GAS BOTTLE STATION [PDF]

Fiabilitate şi Durabilitate, 2015
Paper presents the analize of the working conditions of the emplo that works into a gas station. The main vibration effects to human body are presented, limit values to vibration according to actual legislation, measuring devices used for vibration ...
Ionelia CIOCAN, Dan Florin NITOI, Andrei DIMITRESCU, Zoia APOSTOLESCU   +3 more
doaj  

Definition of Optimal Working Conditions of Solid Oxide Fuel Cell [PDF]

, 2006
Anne-Laure Sauvet, Antoine Henry, C. Barthet   +2 more
openalex   +1 more source