Results 201 to 210 of about 4,218,234 (309)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Diagrams in Essays: Exploring the Kinds of Diagrams Students Generate and How Well They Work

Diagrams in Essays: Exploring the Kinds of Diagrams Students Generate and How Well They Work
Using appropriate diagrams is generally considered efficacious in communication. However, although diagrams are extensively used in printed and digital media, people in general rarely construct diagrams to use in common everyday communication. Furthermore, instruction on diagram use for communicative purposes is uncommon in formal education and, when ...
openaire   +1 more source

Materials Acceleration Platform for Electrochemistry: a Platform for Autonomous Electrochemistry. [PDF]

Npj Mater Degrad
Persaud D, Werezak M, Xu M, Zhou M, Benkel F, Pang X, Attari V, DeCost B, Dale AS, Senior N, Birsan G, Hattrick-Simpers J.   +11 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

FEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli, Carlotta Chiesa, Maher Abou Hachem, Ditte Hededam Welner   +3 more
wiley   +1 more source

Working diagram management sorting timber

Resources and Technology, 2005
openaire   +1 more source

Nonvisual Support for Understanding and Reasoning about Data Structures. [PDF]

Proc SIGCHI Conf Hum Factor Comput Syst
Wimer BL, Kanchi R, Frierson K, Potluri V, Metoyer RA, Mankoff J, Natsuhara M, Wang MX.   +7 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Mechanical Properties and Energy Absorption Characteristics of Ring Lattice Sandwich Structures Under Compressive Load. [PDF]

Materials (Basel)
Wang W, Jiang X, Liao Y, Tian Z.
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

A compositional semantics for Venn diagrams. [PDF]

Linguist Philos
Pickel B, Rabern B.
europepmc   +1 more source