Results 121 to 130 of about 432,619 (299)

The health of working dogs in conservation in Africa. [PDF]

Front Vet Sci, 2023
Earnshaw N, Anderson N, Mackay J, Parker M.   +3 more
europepmc   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Injuries and Associated Factors in Swedish Sporting and Utility Trial Dogs—A Cross-Sectional Study

Animals
Canine sporting competitions, e.g., agility, obedience, rally obedience, and utility trials, e.g., protection, tracking, search, and messenger, are physically and mentally demanding disciplines.
Ann Essner, Catarina Kjellerstedt, Amie L. Hesbach, Helena Igelström   +3 more
doaj   +1 more source

Dog breed selection and factors that shape them : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Zoology at Massey University, Palmerston North, New Zealand [PDF]

, 2016
The aim of this research was to describe human perceptions of dog breeds, New Zealand national dog demographics, and the relationship between aesthetic appeal and physical conformation of dog breeds.
Challand, Tyler J
core  

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Editorial: Our Canine Connection: The History, Benefits and Future of Human-Dog Interactions

Frontiers in Veterinary Science, 2021
Eric G. Strauss, Sandra McCune, Sandra McCune, Evan MacLean, Evan MacLean, Evan MacLean, Evan MacLean, Aubrey Fine   +7 more
doaj   +1 more source

Assessment of Body Condition in Long-Distance Sled Dogs: Validation of the Body Condition Score and Its Association with Ultrasonographic, Plicometric, and Anthropometric Measurements

Veterinary Sciences
This study aimed to validate the 9-point body condition score (BCS) system in sled dogs by assessing its reliability and by comparing it with objective measures including real-time ultrasonography, plicometry, and anthropometry.
Sergio Maffi, Alice Bonometti, Chiara Chiaffredo, Andrea Galimberti, Chiara Barletta, Katia Morselli, Laura Menchetti, Alda Quattrone   +7 more
doaj   +1 more source