Results 101 to 110 of about 432,619 (299)

Diet Analysis for Wildlife Management: Protecting the Cheetah in Namibia [PDF]

, 2015
I spent the summer of 2014 in the genetics laboratory of the Cheetah Conservation Fund (CCF) in Namibia, Africa, to learn about the diets of the carnivores in the surrounding conservancy.
Walsh, Alicia
core   +2 more sources

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Metabolic and Physiological Responses of Trained Working Dogs During the Protection Phase of the “Internationale Gebrauchshunde Prüfungs-Ordnung, Level 1” (IGP1)

Veterinary Sciences
This study aimed to evaluate the trends in physiological and metabolic parameters—such as heart rate (HR), respiratory rate (RR), hematological parameters, blood lactate, and serum enzymes (LDH, AST, and CK)—in seven regularly trained working dogs during
Raffaella Cocco, Sara Sechi, Maria Rizzo, Claudia Giannetto, Federica Arrigo, Maria Luisa Pinna Parpaglia, Giuseppe Piccione, Francesca Arfuso   +7 more
doaj   +1 more source

IMPACT: The Journal of the Center for Interdisciplinary Teaching and Learning. Volume 9, Issue 1, Winter 2020 [PDF]

, 2020
Explicitly established to foreground interdisciplinary teaching and learning, Impact also welcomes evidence and discussion of experiential learning. Often the two – interdisciplinary teaching and experiential learning – co-exist.
Beiter, Eileen, Engbers, Susanna Kelly, Flaisher-Grinberg, Shlomit, Hill, Stephen, Leverone, Cathy, Roybal, Karen R., Smale, Maura A., Sullivan, Megan, Vail, Jeffrey   +8 more
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Editorial: Canine Olfactory Detection

Frontiers in Veterinary Science, 2020
Claire Guest, Cynthia M. Otto, Cynthia M. Otto   +2 more
doaj   +1 more source

Investigation of the Behavioral Characteristics of Dogs Purpose-Bred and Prepared to Perform Vapor Wake® Detection of Person-Borne Explosives

Frontiers in Veterinary Science, 2018
Specialized detector dogs are increasingly being utilized for the detection of modern threats. The Vapor Wake® (VW) dog was developed to create a dog phenotype ideally suited for detecting hand-carried and body-worn explosives. VW dogs (VWDs) are trained
Lucia Lazarowski, Lucia Lazarowski, Pamela Sue Haney, Jeanne Brock, Terry Fischer, Bart Rogers, Craig Angle, Jeffrey S. Katz, L. Paul Waggoner   +8 more
doaj   +1 more source

What lessons can we learn from Babe, a sheep-pig, about inter-cultural adaptation? [PDF]

, 2007
This paper examines the movie Babe to discuss inter-cultural adaptation strategies and the role that affection and trust plays in inter-cultural relations.
Ruffolo, Lara, Sayers, Janet
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Balancing Objectivity and Welfare: Physiological and Behavioural Responses of Guide Dogs During an Independent Certification Protocol

Animals
Guide dogs are essential in supporting the autonomy of blind and visually impaired individuals. Austria is the first country to implement a legally mandated, two-stage certification protocol for the official recognition of guide dogs, assessed by an ...
Viola Faerber-Morak, Lisa-Maria Glenk, Karl Weissenbacher, Annika Bremhorst   +3 more
doaj   +1 more source