Results 91 to 100 of about 4,234,681 (285)

Chagas disease control: deltamethrin-treated collars reduce Triatoma infestans feeding success on dogs.

open access: yes, 2005
Dogs are domestic reservoir hosts of Trypanosoma cruzi, the aetiological agent of Chagas disease. Using an experimental set-up mimicking rural mud-and-thatch houses, we evaluated the effect of deltamethrin-treated dog collars on the feeding success and ...
Reithinger, Richard   +4 more
core   +1 more source

Why do dogs (Canis familiaris) select the empty container in an observational learning task? [PDF]

open access: yes, 2010
Many argue that dogs show unique susceptibility to human communicative signals that make them suitable for being engaged in complex co-operation with humans.
Topál, J.   +11 more
core   +1 more source

The high end of toy motivation in dogs: developmental predictors and relevance for sport and working dogsThe high end of toy motivation in dogs: developmental predictors and relevance for sport and working dogs [PDF]

open access: yesRoyal Society Open Science
Toy-directed play motivation varies significantly among domestic dogs. In some individuals, it reaches such exceptional levels that it exhibits phenomenological parallels with behavioural addictions. This study investigated demographic, developmental and
Alja Mazzini, Stefanie Riemer
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Effects of topical application of fipronil spot-on on dogs against the Chagas disease vector Triatoma infestans.

open access: yes, 2009
We assessed the insecticidal effects of fipronil spot-on applied to experimental dogs on the blood-feeding success and other vital parameters of the Trypanosoma cruzi vector Triatoma infestans.
Reithinger, Richard   +4 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

The Lockdown Diaries of the Working Class

open access: yes, 2022
Collated by the Working Class Collective, The Lockdown Diaries of the Working Class is a beautiful, self-published, illustrated book featuring the diaries of working class people from across the UK and their experiences of life during the first COVID19 ...
The Working Class Collective
core   +2 more sources

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