Results 81 to 90 of about 432,619 (299)

A Randomized Cross-Over Field Study of Pre-Hydration Strategies in Dogs Tracking in Hot Environments

open access: yesFrontiers in Veterinary Science, 2020
The objective of this study was to evaluate 4 pre-exercise hydration strategies (oral water, chicken-flavored water, chicken-flavored oral electrolyte solution, and subcutaneous electrolyte solution) in working dogs conducting rigorous tracking ...
Greta M. Niedermeyer   +13 more
doaj   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Prevalence of Trypanosoma cruzi infection in dogs in the United States: a systematic review and meta-analysis of observational studies (2000–2024)

open access: yesFrontiers in Veterinary Science
BackgroundCanine infection with Trypanosoma cruzi, the causative agent of Chagas disease, is a public health concern in the United States (U.S.), particularly in southern states where triatomine vectors are established.
Victor Agbajelola   +7 more
doaj   +1 more source

The New Zealand Police dogs : a thesis presented in partial fulfilment of the requirements for the degree of Master of Veterinary Studies in Animal Science at Massey University [PDF]

open access: yes, 2002
This study aimed to identify characteristics of dogs to be used by the New Zealand Police Section for their dog breeding and selection programs. Only one scientific paper has been published on selecting dogs specifically for police dog work.
Kyono, Monica
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Spatial working memory in a disappearing object task is impaired in female but not male dogs with chronic osteoarthritis

open access: yesAnimal Cognition
Chronic pain in humans is associated with impaired working memory but it is not known whether this is the case in long-lived companion animals, such as dogs, who are especially vulnerable to developing age-related chronic pain conditions.
Melissa Smith   +2 more
doaj   +1 more source

Animal-Assisted Therapy: Motives and Rewards [PDF]

open access: yes, 2014
Animal-assisted therapy is a complimentary therapy utilized in health care to provide goal-directed therapy using dogs. The purpose of this study was to understand what motivates individuals to being animal-assisted volunteering and rewards that ...
Collins, Kailee Victoria
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Candidatus Bartonella merieuxii, a potential new zoonotic Bartonella species in canids from Iraq. [PDF]

open access: yes, 2012
Bartonellae are emerging vector-borne pathogens infecting erythrocytes and endothelial cells of various domestic and wild mammals. Blood samples were collected from domestic and wild canids in Iraq under the United States Army zoonotic disease ...
Breitschwerdt, Edward B   +7 more
core   +2 more sources

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