Results 71 to 80 of about 4,676,319 (282)

The Penn Vet Working Dog Center Fit to Work Program: A Formalized Method for Assessing and Developing Foundational Canine Physical Fitness

Frontiers in Veterinary Science, 2020
Fit to Work is a formalized working dog foundational physical fitness assessment and development program. The Penn Vet Working Dog Center developed this program to address the needs of working dog handlers, trainers, and programs for simple, effective ...
Brian D. Farr, Brian D. Farr, Meghan T. Ramos, Cynthia M. Otto   +3 more
doaj   +1 more source

Dogs as sources and sentinels of parasites in humans and wildlife, northern Canada [PDF]

, 2008
A minimum of 11 genera of parasites, including 7 known or suspected to cause zoonoses, were detected in dogs in 2 northern Canadian communities. Dogs in remote settlements receive minimal veterinary care and may serve as sources and sentinels for ...
Brett T. Elkin, Douglas P. Whiteside, Thompson, R.C.A., Salb, Amanda L., Barkema, H.W., Black, S.R., Whiteside, D.P., R.C. Andrew Thompson, Kutz, S.J., Amanda L. Salb, Sandra R. Black, J.P. Dubey, Susan J. Kutz, Elkin, B.T., Herman W. Barkema, Dubey, J.P.   +15 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

The high end of toy motivation in dogs: developmental predictors and relevance for sport and working dogsThe high end of toy motivation in dogs: developmental predictors and relevance for sport and working dogs [PDF]

Royal Society Open Science
Toy-directed play motivation varies significantly among domestic dogs. In some individuals, it reaches such exceptional levels that it exhibits phenomenological parallels with behavioural addictions. This study investigated demographic, developmental and
Alja Mazzini, Stefanie Riemer
doaj   +1 more source

Review of How Dogs Work and What is a Dog? [PDF]

Journal of Mammalogy, 2016
Coppinger, R., and M. Feinstein. 2015. How Dogs Work. University of Chicago Press, Chicago, Illinois, xii + 244 pp. + 8 pl. ISBN: 978-0-226-12813-9, price (cloth), $26. Coppinger, R., and L. Coppinger. 2016. What Is a Dog? University of Chicago Press, Chicago, Illinois, xviii + 258 pp. + 16 pl. ISBN: 978-0-226-12794-1, price (cloth), $30. Raymond and
openaire   +1 more source

Endo and Ectoparasites in working dogs

, 2015
The incidence of endo- and ectoparasites of dogs (especially working dogs) was observed in České Budějovice city and its surroundings. Dog faecal samples were collected for examination during December 2013 January 2015.
SRNCOVÁ, Štěpánka
core  

Remission of histiocytic ulcerative colitis in Boxer dogs correlates with eradication of invasive intramucosal Escherichia coli [PDF]

, 2009
BACKGROUND: Historically, histiocytic ulcerative (HUC) (or granulomatous) colitis of Boxer dogs was considered an idiopathic immune-mediated disease with a poor prognosis. Recent reports of dramatic responses to enrofloxacin and the discovery of invasive
Dogan, B., Nicholls, P.K., Simpson, K.W., Davies, D.R., James, F.E., MacDonough, S.P., Mansfield, C.S., Craven, M., O'Hara, A.J.   +8 more
core  

Domestic dogs use contextual information and tone of voice when following a human pointing gesture [PDF]

, 2011
Domestic dogs are skillful at using the human pointing gesture. In this study we investigated whether dogs take contextual information into account when following pointing gestures, specifically, whether they follow human pointing gestures more readily ...
Grassmann, Susanne, Linda Scheider, Tomasello Michael, Tomasello, M., Juliane Kaminski, Tomasello, M. ; https://orcid.org/, Scheider, Linda, Scheider Linda, Tomasello, Michael, Scheider, L., Kaminski, J. ; https://orcid.org/, Michael Tomasello, Grassmann Susanne, Kaminski Juliane, Grassmann, S. ; https://orcid.org/, Kaminski, Juliane, Susanne Grassmann   +16 more
core   +1 more source