Results 51 to 60 of about 432,619 (299)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Scent detection dogs detect a species of hard tick, Dermacentor albipictus, with comparable accuracy and efficiency to traditional tick drag surveys

Parasites & Vectors
Background Accurate surveillance data are critical for addressing tick and tick-borne pathogen risk to human and animal health. Current surveillance methods for detecting invading or expanding tick species are limited in their ability to scale ...
Troy Koser, Aimee Hurt, Laura Thompson, Alyson Courtemanch, Benjamin Wise, Paul Cross   +5 more
doaj   +1 more source

International Veterinary Epilepsy Task Force Consensus Proposal: Diagnostic approach to epilepsy in dogs [PDF]

, 2015
This article outlines the consensus proposal on diagnosis of epilepsy in dogs by the International Veterinary Epilepsy Task Force. The aim of this consensus proposal is to improve consistency in the diagnosis of epilepsy in the clinical and research ...
A Pákozdy, Akos Pakozdy, Andrea Fischer, Andrea Tipold, AT Berg, BG Licht, C Brauer, C Brauer, CL Mariani, Clare Rusbridge, EE Patterson, EE Patterson, G Urkasemsin, Heidrun Potschka, Holger A. Volk, J Guevar, Jacques Penderis, JJ Lin, JL Gill, JW Schmidley, Karen Muñana, Kaspar Matiasek, KJ Ekenstedt, L Arrol, LM Mellema, Luisa De Risio, M Armaşu, M Berendt, M Podell, M Schwartz, M Schwartz, M Wolf, Martí Pumarola Batlle, Mette Berendt, Michael Podell, N Shihab, Ned Patterson, O Devinsky, Paul JJ. Mandigers, PM Smith, R Edwards, R Erro, R Gonçalves, R Poma, R Zimmermann, RMA Packer, Robyn Farqhuar, Rowena MA Packer, RS Fisher, RS Fisher, S Shorvon, Sam Long, Simon Platt, Sofie Bhatti, TM Ghormle, V Hülsmeyer, Veronika Stein, WB Thomas, WW Bush, YC Huang   +59 more
core   +8 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Cytological Findings of 140 Bile Samples from Dogs and Cats and Associated Clinical Pathological Data [PDF]

, 2015
BACKGROUND: Cholecystocentesis can be part of the diagnostic workup of hepatobiliary disease in small animals, but literature on cytological evaluation of bile is scant.
Boomkens, Brain, Braun, Center, Clark, Crews, Flatland, Geigy, Kook, Lawrence, Neel, Ramery, Savary-Bataille, Sung, Voros, Wagner, Weiss   +16 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Campylobacter species in dogs and cats and significance to public health in New Zealand : a thesis in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Massey University, Palmerston North, New Zealand [PDF]

, 2016
Campylobacter spp. are a major cause of bacterial gastroenteritis in people in the developed world, including New Zealand. Many sources and transmission routes exist, as these bacteria are common in animals and the environment. C.
Bojanić, Krunoslav
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Effectiveness of canine‐assisted surveillance and human searches for early detection of invasive spotted lanternfly

Ecosphere
Prevention and early detection of invasive species are championed as the most cost‐effective and efficient strategies for reducing or preventing negative impacts on ecosystems.
Angela K. Fuller, Ben C. Augustine, Eric H. Clifton, Ann E. Hajek, Arden Blumenthal, Josh Beese, Aimee Hurt, Carrie J. Brown‐Lima   +7 more
doaj   +1 more source

Everyday behaviour in dogs [PDF]

, 2015
The absolute majority of dogs are kept as companion animals. Dogs kept as family pets are frequently exposed to noisy and crowded environments, and often have to interact with unfamiliar dogs and humans.
Eken Asp, Helena
core