Results 191 to 200 of about 56,587 (265)

Evaluating support for the debrief process for paediatric oncology trainee doctors and newly appointed consultants after child death. [PDF]

BMJ Paediatr Open
Senanayake U, Aubugeau-Williams P, Barnard G.   +2 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Work meaning in medicine: a comparative investigation across training stages. [PDF]

Front Med (Lausanne)
Kovaks N, Lipshits-Braziler Y, Amram-Vaknin S, Gutentag T.   +3 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Briefing document on Theological Education following the Working Class Clergy Wellbeing Project

As part of wider Living Ministry longitudinal research into clergy wellbeing, Ministry Division commissioned a satellite project into the wellbeing of working-class clergy in October 2022.
Fry, Alex, Jagger, Sharon, Tyndall, Becky   +2 more
core  

Perpetual connectivity as digital labor: a conceptual reframing of the always-on work culture. [PDF]

Front Public Health
Mdhluli NI.
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

The moderating role of job satisfaction in the relationship between workplace violence and depression among accountants. [PDF]

Front Public Health
Kocamiş TU, Kazan G.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Promoting Flourishing at Work: Innovations in Positive Work and Organisational Psychology. [PDF]

Behav Sci (Basel)
Hart R, Hart D.
europepmc   +1 more source