Results 141 to 150 of about 5,581,186 (359)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Water, air and fire at work in Hero's machines [PDF]
, 2011 Known as the Michanikos, Hero of Alexandria is considered the inventor of the world's first steam engine and of many other sophisticated devices. Here we discuss three of them as described in his book "Pneumatica". These machines, working with water, air
Sparavigna, Amelia Carolina
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Prototype solar heating and combined heating and cooling systems [PDF]
Designs were completed, hardware was received, and hardware was shipped to two sites. A change was made in the heat pump working fluid.
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Preliminary results from a four-working space, double-acting piston, Stirling engine controls model [PDF]
A four working space, double acting piston, Stirling engine simulation is being developed for controls studies. The development method is to construct two simulations, one for detailed fluid behavior, and a second model with simple fluid behaviour but ...
Daniele, C. J., Lorenzo, C. F.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Choosing the Most Suitable Working Fluid for a CTEC
EnergiesThis study aims to explore additional fluids beneficial for coastal thermal energy converter (CTEC) operation. Ammonia’s thermodynamic properties, characterized by higher condensation temperatures and pressures, demand significantly elevated operating ...
Aliet Achkienasi +3 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Meitian dizhi yu kantanObjectiveThe commingled production of coalbed methane (CBM) serves as a significant means to increase single-well production. However, production practices reveal that the commingled production of CBM exhibits complex and varied effects and controlling ...
Chen GUO +10 more
doaj +1 more source