Results 131 to 140 of about 287,037 (310)

Fluid-dynamical parameters control for atomized slip pneumatic conveying

, 2010
Paper presented at the 7th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Turkey, 19-21 July, 2010.One of the most important problems in ceramic industrial processes is the atomized slip conveying.
SACCANI, CESARE, Bianchini, A., BIANCHINI, AUGUSTO, Saccani, C.   +3 more
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Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Choosing the Most Suitable Working Fluid for a CTEC

Energies
This study aims to explore additional fluids beneficial for coastal thermal energy converter (CTEC) operation. Ammonia’s thermodynamic properties, characterized by higher condensation temperatures and pressures, demand significantly elevated operating ...
Aliet Achkienasi, Rodolfo Silva, Edgar Mendoza, Luis D. Luna   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Influence of working fluid on ORC with low temperature geothermal source – Case study geothermal power plant “Babina Greda” [PDF]

, 2014
Paper presented to the 10th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, Florida, 14-16 July 2014.In 1998 the Energy Institute “Hrvoje Požar” prepared a Program of Geothermal Energy Usage in the Republic of Croatia ...
Guzović, Z., Sakoman, I., Lončar, D.
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An analytical method for the desorption superposition effect in commingled production of coalbed methane and its application: A case study of the Xiaotun mine field in western Guizhou Province, China

Meitian dizhi yu kantan
ObjectiveThe commingled production of coalbed methane (CBM) serves as a significant means to increase single-well production. However, production practices reveal that the commingled production of CBM exhibits complex and varied effects and controlling ...
Chen GUO, Yan JI, Chenyi ZHAO, Lingling LU, Xinhang YU, Junzhe GAO, Houqiang LI, Xuyang ZHANG, Xiang WANG, Hongbin HE, Runhan ZHANG   +10 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Water as a thermoacoustic working fluid

, 1988
This short report, addressed only to the thermoacoustic cognoscenti, discusses thermodynamic and transport properties of water with emphasis on water's virtues as a thermoacoustic working fluid.
Swift, G.W.
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