Results 111 to 120 of about 5,382,061 (295)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Effect of working-fluid mixtures on organic Rankine cycle system performance : heat transfer and cost analysis [PDF]

, 2015
Papers presented to the 11th International Conference on Heat Transfer, Fluid Mechanics and Thermodynamics, South Africa, 20-23 July 2015.A thermodynamic limitation of single-component working fluids in organic Rankine cycles (ORCs) is the large exergy ...
Markides, C.N., Oyewunmi, O.A.
core   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

Molecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara, Kosuke Murakami, Shiro Takamatsu, Akiko Kanto, Seiichi Mori, Tomoyuki Otani, Kazuko Sakai, Yasushi Kotani, Kazuto Nishio, Kaoru Abiko, Noriomi Matsumura   +10 more
wiley   +1 more source

Choosing the Most Suitable Working Fluid for a CTEC

Energies
This study aims to explore additional fluids beneficial for coastal thermal energy converter (CTEC) operation. Ammonia’s thermodynamic properties, characterized by higher condensation temperatures and pressures, demand significantly elevated operating ...
Aliet Achkienasi, Rodolfo Silva, Edgar Mendoza, Luis D. Luna   +3 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

An analytical method for the desorption superposition effect in commingled production of coalbed methane and its application: A case study of the Xiaotun mine field in western Guizhou Province, China

Meitian dizhi yu kantan
ObjectiveThe commingled production of coalbed methane (CBM) serves as a significant means to increase single-well production. However, production practices reveal that the commingled production of CBM exhibits complex and varied effects and controlling ...
Chen GUO, Yan JI, Chenyi ZHAO, Lingling LU, Xinhang YU, Junzhe GAO, Houqiang LI, Xuyang ZHANG, Xiang WANG, Hongbin HE, Runhan ZHANG   +10 more
doaj   +1 more source

Fluid-motion effects on the dynamics of thermal frontal polymerization

Thermal frontal polymerization (FP) is a process that rapidly converts liquid monomer solutions into solid polymers via self-sustaining exothermic reaction fronts. It is a promising method for polymer manufacturing because it is fast and energy-efficient.
78th APS Division of Fluid Dynamics Annual Meeting 2025, Faragalla, Maged, Papalexandris, Miltiadis   +2 more
core  

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

XSEDE Security Working Group Charter V1.1

, 2016
Submitted by Janet Brown (brown@psc.edu) on 2016-04-04T15:58:46Z No. of bitstreams: 1 XSEDE Security Working Group Charter-v1.1.pdf: 686647 bytes, checksum: de3b8f49e728ded067cf1d8271c010c2 (MD5)Made available in DSpace on 2016-04-04T15:58:47Z (GMT). No.
XSEDE Security Working Group
core   +1 more source

Thermodynamic analysis of basic and regenerative organic rankine cycles usingdry fluids from waste h

Journal of Thermal Engineering, 2018
The organic Rankine cycle (ORC), which generates electric energy using low temperature heat sources, is a promising technology in energy production sector.
E. Ozdemir, M. Kilic
doaj