Results 101 to 110 of about 5,382,061 (295)

A Review of Thermal Aspects and System Coupling in Thermoelectric Generators

Energies
There has been a rising trend for recovering waste heat, especially after the invention of new types of semiconductors. Among all available utilization options, thermoelectric generation (TEG) systems are promising for recovering waste heat ...
Samarjeet Kumar, Purushottam Kumar Singh, Santosh Kr. Mishra, Ram Krishna Upadhyay, Gyan Wrat   +4 more
doaj   +1 more source

Large Eddy Simulation and Thermodynamic Design of the Organic Rankine Cycle Based on Butane Working Fluid and the High-Boiling-Point Phenyl Naphthalene Liquid Heating System. [PDF]

Entropy (Basel), 2022
Davidy A.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Visualization Experimental Study on Silicon-Based Ultra-Thin Loop Heat Pipe Using Deionized Water as Working Fluid. [PDF]

Micromachines (Basel), 2021
Song W, Xu Y, Xue L, Li H, Guo C.
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Numerical study of thermally stratified flows of a fluid overlying a highly porous material

, 2014
In this talk we are concerned with thermally stratified flows in domains that contain a macroscopic interface between a highly porous material and a pure-fluid domain.
Antoniadis, Panagiotis, Papalexandris, Miltiadis, APS 67h Annual Meeting of the Division of Fluid Dynamics   +2 more
core  

Experimental investigation of Minimum Quantity Lubrication (MQL) of coconut oil based Metal Working Fluid

, 2019
Minimum Quantity Lubrication (MQL) is a technique of applying fine mists of Metal Working Fluid (MWF), instead a flood of it. This paper describes performance evaluation of novel coconut oil based MWF, during turning of AISI 304 Austenitic Stainless ...
Sarmilan, N., Wickramasinghe, K. C., Herath, H. M. C. M., Fernando, W. L. R, Perera, G. I. P.   +4 more
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source