Results 101 to 110 of about 1,180,308 (314)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
METHOD OF MONITORING CHARGE CONDITION OF HEAT PUMP SYSTEM [PDF]
, 2019 A heat-pump circuit may include an indoor heat exchanger, an outdoor heat exchanger, a compressor adapted to circulate a working fluid between the indoor and outdoor heat exchangers, and an expansion device disposed between the indoor and outdoor heat ...
Alsaleem, Fadi M., Hemmelgarn, Gregg M.
core +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Liquid-metal-piston MHD generator [PDF]
, 1969 Magnetohydrodynamic generator uses a slug or piston of liquid potassium as the working fluid. An expanding vapor of the metal is allowed to reciprocate the liquid-metal-piston through a magnetic field and the expansion energy is converted directly into ...
Palmer, J. P.
core +1 more source
Fluid model for a network operating under a fair bandwidth-sharing policy
, 2004 We consider a model of Internet congestion control that represents the randomly varying number of flows present in a network where bandwidth is shared fairly between document transfers.
A Fair +3 more
core +5 more sources
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Organic rankine cycle with positive displacement expander and variable working fluid composition [PDF]
, 2016 Organic Rankine Cycles are often used in the exploitation of low-temperature heat sources. The relatively small temperature differential available to these projects makes them particularly vulnerable to changing ambient conditions, especially if an air ...
Collings, Peter, Yu, Zhibin
core
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Thermodynamic analysis of the partially evaporating trilateral cycle [PDF]
, 2013 The potential of Organic Rankine Cycles (ORC) to recover low grade waste heat is well known. The high heat recovery potential is partially attributed to a good match of the temperature profiles between working fluid and waste heat stream in the ...
De Paepe, Michel +2 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source