Results 81 to 90 of about 1,180,308 (314)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Thermodynamic Perfomance Comparison of Working Fluids Based on Organic Rankine Cycle in Waste Power Plants [PDF]

open access: yesE3S Web of Conferences
The use of alternative fuels, other than fossil fuels, is an interesting issue for power generation today. The power plant option used is a waste power plant that utilizes the heat exhausted from the garbage.
Kopong Ola Kornelis   +3 more
doaj   +1 more source

Systematic Stochastic Reduction of Inertial Fluid-Structure Interactions subject to Thermal Fluctuations

open access: yes, 2012
We present analysis for the reduction of an inertial description of fluid-structure interactions subject to thermal fluctuations. We show how the viscous coupling between the immersed structures and the fluid can be simplified in the regime where this ...
Atzberger, Paul J., Tabak, Gil
core   +1 more source

Working Knowledge for Fluid Management

open access: yesTHE JOURNAL OF JAPAN SOCIETY FOR CLINICAL ANESTHESIA, 2010
麻酔中の輸液は血管内輸液,間質への輸液,細胞内への輸液の3本立てで考える.細胞外液製剤はブドウ糖以外の糖を浸透圧調整のため含んでいる製剤が容量効果と利尿効果をもっているので使いやすい.ヒドロキシエチルスターチ(HES)は血管内輸液として適切である.膠質浸透圧は測定膜,内皮細胞臓器特異性,病態を考慮する必要がある.HESには抗炎症作用があり,末梢循環を維持することができる.6% HES70は腎や止血凝固への影響は最も少ない.輸液のモニターとして尿量が臨床的である.圧モニターとしてのCVPより経食道心エコー下の容量負荷を重視した考え方がある.混合静脈血酸素飽和度や乳酸値は輸液を含めた周術期管理の総合的なモニターとして重要である.
openaire   +2 more sources

Hazards of organic working fluids [PDF]

open access: yes, 1977
We present several brief reviews on working fluids proposed for use in organic Rankine and bi-phase bottoming cycles. There are several general problems with many organic working fluids: flammability, toxicity, and a tendency to leak through seals.
openaire   +2 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Optimization and Analyses of an Organic Rankine Cycle Combined System Utilizing the Waste Heat of Gas Turbine Exhaust

open access: yesZhileng xuebao, 2019
In this study a combined organic Rankine cycle system is proposed to utilize the waste heat of gas turbine exhaust. The thermodynamic properties of the system are analyzed in detail.
Ma Shuaijie, Lin Wensheng
doaj  

Collective performance of a finite-time quantum Otto cycle

open access: yes, 2019
We study the finite-time effects in a quantum Otto cycle where a collective spin system is used as the working fluid. Starting from a simple one-qubit system we analyze the transition to the limit cycle in the case of a finite-time thermalization. If the
Cejnar, Pavel   +2 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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