Results 61 to 70 of about 2,005,023 (278)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Frontiers in Human Neuroscience, 2019 In working memory (WM), the ability to concurrently integrate different types of information and to maintain or manipulate them promotes the flow of ongoing tasks. WM is a key component of normal human cognition.
Zhiting Ren +10 more
doaj +1 more source
The effect of laughter yoga on working memory
The European Journal of Humour Research, 2022 A growing body of evidence suggests that there is a link between laughter and memory. However, no research has been done to show a link between simulated laughter (laughter yoga) and the enhancement of working memory.
Md. Shahinoor Rahman, Farida Binte Wali
doaj +1 more source
Prefrontal Activity Links Nonoverlapping Events in Memory [PDF]
, 2013 The medial prefrontal cortex (mPFC) plays an important role in memory. By maintaining a working memory buffer, neurons in prelimbic (PL) mPFC may selectively contribute to learning associations between stimuli that are separated in time, as in trace fear
Diba, Kamran +3 more
core +2 more sources
Targeting p38α in cancer: challenges, opportunities, and emerging strategies
Molecular Oncology, EarlyView.p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Parietal contributions to visual working memory depend on task difficulty
Frontiers in Psychiatry, 2012 The nature of parietal contributions to working memory (WM) remain poorly understood but of considerable interest. We previously reported that posterior parietal damage selectively impaired WM probed by recognition (Berryhill & Olson, 2008a).
Kevin T. Jones, Marian eBerryhill
doaj +1 more source
The “working” of working memory
Dialogues in Clinical Neuroscience, 2013 This review examines the evidence for a neurobiological explanation of executive functions of working memory. We suggest that executive control stems from information about task rules acquired by mixed selective, adaptive coding, multifunctional neurons in the prefrontal cortex.
openaire +3 more sources
Faster Isn't Necessarily Better: The Role of Individual Differences on Processing Words with Multiple Translations [PDF]
, 2007 Words that can translate several ways into another language have only recently been examined in studies of bilingualism. The present study examined how individual differences in working memory span and interference affect the processing of such words ...
Smith, Courtney J.
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
The Impact of Auditory Working Memory Training on the Fronto-Parietal Working Memory Network
Frontiers in Human Neuroscience, 2012 Working memory training has been widely used to investigate working memory processes. We have shown previously that visual working memory benefits only from intra-modal visual but not from across-modal auditory working memory training.
Julia eSchneiders +6 more
doaj +1 more source