Results 81 to 90 of about 5,643,683 (390)
Do multiplication and division strategies rely on executive and phonological working memory resources? [PDF]
The role of executive and phonological working-memory resources in simple arithmetic was investigated in two experiments. Participants had to solve simple multiplication problems (e.g., 4 x 8; Experiment 1) or simple division problems (e.g., 42 : 7 ...
Imbo, Ineke, Vandierendonck, André
core +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Working memory load elicits attentional bias to threat [PDF]
Anxious individuals tend to show attentional bias to threats and dangers; this is usually in-terpreted as a specific bias in threat-processing. However, they also tend to show general working memory and cognitive control impairments. We hypothesised that
Booth, Robert, Sharma, Dinkar
core
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Objective: The present study was an attempt to examine the difference in the profile of working memory, auditory working memory, and spatial working memory between drug, stimulant, and methadone abusers and normal people.
Ahmad Alipour+2 more
doaj
Examining the link between information processing speed and executive functioning in multiple sclerosis [PDF]
Slowed information processing speed (IPS) is frequently reported in those with multiple sclerosis (MS), and at least 20% are compromised on some aspect of executive functioning also.
Drew, Margaret A.+2 more
core +2 more sources
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Faster Isn't Necessarily Better: The Role of Individual Differences on Processing Words with Multiple Translations [PDF]
Words that can translate several ways into another language have only recently been examined in studies of bilingualism. The present study examined how individual differences in working memory span and interference affect the processing of such words ...
Smith, Courtney J.
core
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source