Results 161 to 170 of about 1,232,429 (290)

Refining the Model: Coach-Informed Adaptations to Integrative Health and Wellness Coaching for People With Intellectual and Developmental Disabilities. [PDF]

Am J Lifestyle Med
Smith AM, Prelock PA, Pettineo S, Daniels S, Medeiros S, Westervelt K.   +5 more
europepmc   +1 more source

Dual process impairments in reinforcement learning and working memory systems underlie learning deficits in physiological anxiety

Jennifer Senta, Sonia J. Bishop, Anne Collins   +2 more
openalex   +1 more source

Explaining the high working memory capacity of gifted children: 
 Contributions of processing skills and executive control

, 2018
Alexandre Aubry, Corentin Gonthier, Béatrice Bourdin   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

The moment of youth: learning from youth-led research on sexual and reproductive health and rights (SRHR) in Malawian and Zambian settings. [PDF]

Res Involv Engagem
Kakal T, van Tuijl C, Mikwala K, Junior JZ.   +3 more
europepmc   +1 more source

Basic numerical processing in genetic syndromes: The role of visuo-spatial processing and working memory.

, 2017
Laurence Rousselle, Lucie Attout, Line Vossius, Marie‐Pascale Noël   +3 more
openalex   +1 more source

Association of diabetes risk with changes in memory, working memory, and processing speed among older adults [PDF]

Jungjoo Lee, Junhyoung Kim, Sang Joon An
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Health inequalities tackled through intersectoral collaboration: longitudinal process issues and insights. [PDF]

Health Promot Int
Woodall J, Davies P, Woodward J, Coan S.
europepmc   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source