Results 61 to 70 of about 12,358,779 (298)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Process querying: Enabling business intelligence through query-based process analytics [PDF]
, 2017 Highlights\ud \ud - A framework for designing process querying methods is proposed\ud \ud - The framework is positioned for broader Process Analytics and Business Intelligence\ud \ud - The framework is grounded in use cases from the Business Process ...
Aalst, WMP Wil van der +19 more
core +2 more sources
Problematic Issues of Creation of High-Powered Gas and Gas-Diesel Engines
Механика машин, механизмов и материалов, 2018 The creation of modern high-powered gas and gas-diesel engines is associated with the solution of two main tasks – the elimination of abnormal combustion and reduction of engine thermal factor. The paper discusses ways to reduce exhaust gas temperatures,
Sergey V. Bakhmutov +3 more
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
XSEDE Security Working Group Charter V1.1
, 2016 Submitted by Janet Brown (brown@psc.edu) on 2016-04-04T15:58:46Z No. of bitstreams: 1 XSEDE Security Working Group Charter-v1.1.pdf: 686647 bytes, checksum: de3b8f49e728ded067cf1d8271c010c2 (MD5)Made available in DSpace on 2016-04-04T15:58:47Z (GMT). No.
XSEDE Security Working Group
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Working memory capacity as a dynamic process
Frontiers in Psychology, 2013 A well-known characteristic of working memory is its limited capacity. The source of such limitations, however, is a continued point of debate.
Vanessa R Simmering, Sammy ePerone
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Public Service Broadcasting as a Public Good: Challenges in the Digital Era
Medijske Studije, 2015 This article presents a summary of the most important standpoints of the economic debate about public service broadcasting as a public good, and its provision in both the analogue and digital age of broadcasting.
Ivana Andrijašević
doaj
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source