Results 91 to 100 of about 2,216,812 (309)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
This research explored the effect of different presentation orders on processing time and time estimation, from the perspective of verbal working memory dual-task mode task.
Y.W. Chen +5 more
core
Problems regarding the exploitation of apprentices with student status in Indonesia still occur frequently, especially in the relationship between employers and apprentices with student status.
Sahrul
doaj +1 more source
This research has attemF€d ro demonstrate the time usingori€ntations of Tirkish ma.nagers. The sample group of 100 managen weredrawn from various sectors (in both public and private). Data were collectedby two kinds of netlods: A questionnaire and with face to face interviews.As a conclusion of the research it si det€rmined ihai most of the managers ...
UZUNÇARŞILI, Ülkü +1 more
openaire +2 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Health care staff's opinions about an individually controlled and flexible working time arrangement
Introduction In the health care sector shift work is common and a variety of flexible working hour arrangements have been implemented and evaluated.
Kristianstad University. +3 more
core
Certain forms of working time in Serbia in the light of European directive 2003/88 and comparative law [PDF]
The matter of working time is an essential in labour law, considering dignified work as a labour work principle. It took a long time to achieve the standard of eight hours of work, eight hours of free time and eight hours of sleeping.
Rajić-Ćalić Jovana
doaj
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Working Time and Employment under Uncertainty [PDF]
The standard literature on working time has modelled the decisions of firms in a deterministic framework in which firms can choose between employment and overtime (given mandated standard hours).
Chen, Yu-Fu, Funke, Michael
core

