The development and initial validation of a new working time scale for full-time workers with non-standard schedules. [PDF]
BMC Public Health, 2022 Cavallari JM +7 more
europepmc +1 more source
Designing the Optimal Length of Working Time [PDF]
How many hours per week should workers in the United States and Germany spend at their paying jobs? The present paper addresses this question by constructing policymakers’ reaction functions capable of modelling the optimal length of working time as a ...
Antonio Garofalo +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Association between Working Time and Burnout Syndrome in Peruvian Military during the Second Epidemic Wave of COVID-19. [PDF]
Int J Environ Res Public Health, 2022 Valladares-Garrido MJ +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Effect of simulation-based stratified first aid training on physicians: a cohort study stratified by clinical working time and disciplinary background. [PDF]
BMC Med EducYang X +5 more
europepmc +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Working time distribution and administrative burden in Austrian community health nursing: A cross-sectional survey. [PDF]
Int J Nurs Stud AdvKovacevic RM, Behrens DA, Hyll W.
europepmc +1 more source
Spillover and crossover effects of working time demands on work-life balance satisfaction among dual-earner couples: the mediating role of work-family conflict. [PDF]
Curr Psychol, 2022 Lott Y, Wöhrmann A.
europepmc +1 more source
Added worker effect revisited through the French working time reduction experiment [PDF]
This paper studies the impact of the French working time reduction experiment on the family labour supply. I expanded on the conventional added worker effect in order to analyse successively the effect of the ''35 hours'' on two dimensions of the spouse ...
Matthieu Bunel
core