Results 31 to 40 of about 507,478 (266)
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Caregiver burden among working women and homemakers taking care of psychiatric patients
Industrial Psychiatry Journal, 2021 Background: Caregiver burden is defined as the physical, psychological or emotional, social, and financial problem that can be experienced by the members of family caring for impaired person.
Navneet Kaur +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Information for Social Change, 1996 In spite of over 30 years of being blockaded, literacy in Cuba has gone up from 1. 9 per cent before the Revolution to 98 per cent. In nearby Haiti 80 per cent of the population are illiterate.
John Pateman
doaj +1 more source
Role of Handicrafts in Entrepreneurship of Handicrafts Graduates of Kashan University [PDF]
Jilvah-i hunar, 2016 Synthetic arts are objective crystallization of culture and artistic symbols; they are popular and applied arts with their own patterns and originality and have always been presented as an important and critical factor in Iran's economy.
صدیقه کیانی, s kiani selmi
doaj +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
مجله دانشگاه علوم پزشکی بیرجند, 2021 Background and Aims: Happiness and vitality are among the most important and effective components in the process of human life, without which activity, creativity, initiative, invention, and healthy life cannot be created.
Maryam Bahlgerdi +3 more
doaj
Pengaruh Asupan Protein dan Zat Besi (Fe) terhadap Kadar Hemoglobin pada Wanita Bekerja
Jurnal Kesehatan, 2017 Anemia is a condition where the hemoglobin (Hb) is lower than the normal value according to age and sex of a person caused by certain factors, including intake of nutrients one protein and iron, with the percentage of women in Indonesia who have anemia ...
Agus Hendra Al Rahmad
doaj +1 more source
Business: Theory and Practice, 2023 In high-risk situations like the Covid-19 epidemic, it is believed that perceived income adequacy, family support,financial anxiety, and tax non-compliance have a strong relationship.
Priandhita Sukowidyanti Asmoro
doaj +1 more source