Results 71 to 80 of about 409,228 (301)
Wake Forest Sigma Chi Derby Days
Female student falls into water, while another balances on plank, as part of Derby Days, sponsored by Wake Forest's Sigma Chi fraternity.No date on ...
core
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
In the present article, a critical and historical análisis of the antecedents of the process of motivation is made, from the theoretical and methodological point of view.
Luis Alfredo González Collera
doaj
COMPARATIVE ANALYSIS OF IN SITU AND PERI COLUMN FORMS AGAINST COST AND TIME
Cost and time efficiency are key factors in the success of construction projects, particularly in repetitive column formwork works in multi-story buildings.
Natasya Maria Delica, Sri Rahayu
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
SHE enters, deliberately, gravely, without affectation, circumspect in her motions (as she's been taught), not stamping too loud, nor dragging her legs after her, but advancing sedately, discreetly, glancing briefly at the empty rumpled bed, the cast-off nightclothes. She hesitates. No. Again. She enters.
openaire +1 more source
Liver organoids: modelling complexity in homeostasis and disease
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Porcelain Prototypes: Attributing the Models of Ural Art Iron Casting
This article considers one of the most relevant issues in the study of art casting from cast iron. Due to the fact that the administration and owners of the Kasli Iron Works responded in their strategies to the tastes of different consumers and also ...
Kseniya Aleksandrovna Gileva
doaj +1 more source

