Results 81 to 90 of about 409,228 (301)

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Y-Bridge photograph

open access: yes, 1935
This image of the Y-Bridge in Zanesville, Ohio, shows a view of the bridge's Y-junction looking toward the northeast and the Muskingum River. The Y-Bridge is located at the confluence of the Muskingum and Licking rivers, connecting Zanesville with ...
Works Progress Administration
core  

“I Have All the Time in the World”: Bernadette Mayer’s Being in Time

open access: yesHumanities
This essay argues that several of Bernadette Mayer’s major works foreground and develop experiences of subjective time as moments of resistance to the standardizing force of objective clock and calendric time that governs daily material existence. Basing
Amy Moorman Robbins
doaj   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Critical Revolutionary Praxis in the Neoliberal University

open access: yesWorkplace, 2018
I would like to begin with some reflections on the theme of this double issue of Works and Days and Cultural Logic, Transforming Praxis in and beyond the University. The phrase, “transforming praxis,” which obviously refers to Marx’s work, is a pleonasm.
Gary Zabel
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Sculptural Images of Yakushi Nyorai

open access: yesЕжегодник Япония, 2022
Yakushi Nyorai figures form the central theme of the present work, which introduces superb creations of Asuka, Nara, Heian sculptors that survive in our days in the temples of ancient capitals of Japan.
Y. Kuzhel
doaj  

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

THE DAILY LIFE OF THE OLD ISTANBUL REFLECTED IN THE MANSION OF IBRAHIM EFENDI

open access: yesZeitschrift für die Welt der Türken, 2015
Samiha Ayverdi is a writer who had important contribution in Turkish literature producing thirty six works. Ayverdi, during her lifetime witnessed Balkan war, Tripoli war, World War, War of Independence Westernization process was experienced in all its ...
Sevgül TÜRKMENOĞLU
doaj  

Introduction: In Search of Digital Feminisms

open access: yesLateral, 2013
Edited by Katherine Behar and Silvia Ruzanka, In Search of Digital Feminisms includes five essays and the editors’ introduction that suggests we play with the shift from surfing to searching to what is fast becoming the offer, if not the intrusion, of ...
Patricia Ticineto Clough
doaj   +1 more source

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